Human HEF1 (NEDD9) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NEDD9
Locus ID	4739
Kit Components	GA103163G1, HEF1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103163G2, HEF1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103163G3, HEF1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001142393, NM_001271033, NM_006403, NM_182966, NR_073131
Synonyms	CAS-L; CAS2; CASL; CASS2; HEF1
Summary	The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

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