Human IL1RAP activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	IL1RAP
Locus ID	3556
Kit Components	GA102374G1, IL1RAP gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102374G2, IL1RAP gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102374G3, IL1RAP gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001167928, NM_001167929, NM_001167930, NM_001167931, NM_002182, NM_134470, NM_001364879, NM_001364880, NR_157353, NM_001364881, NR_157352
Synonyms	C3orf13; IL-1RAcP; IL1R3
Summary	This gene encodes a component of the interleukin 1 receptor complex, which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in membrane-bound and soluble isoforms differing in their C-terminus. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress. [provided by RefSeq, Jul 2018]

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