Human NMDAR1 (GRIN1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GRIN1
Locus ID	2902
Kit Components	GA101958G1, NMDAR1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101958G2, NMDAR1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101958G3, NMDAR1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000832, NM_001185090, NM_001185091, NM_007327, NM_021569
Synonyms	GluN1; MRD8; NMD-R1; NMDA1; NMDAR1; NR1
Summary	The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]

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