Human Flt3 ligand (FLT3LG) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	FLT3LG
Locus ID	2323
Kit Components	GA101631G1, Flt3 ligand gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101631G2, Flt3 ligand gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101631G3, Flt3 ligand gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001204502, NM_001204503, NM_001278637, NM_001278638, NM_001459
Synonyms	FL; FLT3L
Summary	Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).[supplied by OMIM, Jan 2011]

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