Human FLI1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	FLI1
Locus ID	2313
Kit Components	GA101622G1, FLI1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101622G2, FLI1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101622G3, FLI1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001167681, NM_001271010, NM_001271012, NM_002017
Synonyms	EWSR2; SIC-1
Summary	This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

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