Human Arrestin C (ARR3) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ARR3
Locus ID	407
Kit Components	GA100296G1, Arrestin C gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA100296G2, Arrestin C gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA100296G3, Arrestin C gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_004312
Synonyms	ARRX
Summary	The protein encoded by this gene is a non-visual arrestin which binds to agonist-activated, phosphorylated G protein-coupled receptors. This binding uncouples the receptor from the heterotrimeric G protein, resulting in termination of the G protein-coupled receptor signaling. The encoded protein also is a part of the centrosome, interacting with gamma-tubulin to help regulate proper centrosome function. [provided by RefSeq, May 2016]

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