UACA (NM_001008224) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC222247L3V
- LentiORF®
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Lenti ORF particles, UACA (Myc-DDK-tagged)-Human uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 21,660.00
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Specifications
Product Data | |
Product Name | UACA (NM_001008224) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | NUCLING |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_001008224 |
ORF Size | 4209 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC222247).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001008224.1 |
RefSeq Size | 7096 bp |
RefSeq ORF | 4212 bp |
Locus ID | 55075 |
MW | 161.3 kDa |
Gene Summary | This gene encodes a protein that contains ankyrin repeats and coiled coil domains and likely plays a role in apoptosis. Studies in rodents have implicated the encoded protein in the stimulation of apoptosis and the regulation of mammary gland involution, in which the mammary gland returns to its pre-pregnant state. This protein has also been proposed to negatively regulate apoptosis based on experiments in human cell lines in which the protein was shown to interact with PRKC apoptosis WT1 regulator protein, also known as PAR-4, and inhibit translocation of the PAR-4 receptor. Autoantibodies to this protein have been identified in human patients with panuveitis and Graves' disease. Differential expression of this gene has been observed in various human cancers. [provided by RefSeq, May 2017] |
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