UACA (NM_001008224) Human Untagged Clone
CAT#: SC301265
UACA (untagged)-Human uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA), transcript variant 2
CNY 27,080.00
Product images
![](https://cdn.origene.com/img/defaults-img.jpg)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | NUCLING |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>SC301265 representing NM_001008224.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGATGAACTGTTGGTTTTCTTGTACTCCTAAGAACAGACATGCAGCAGATTGGAATAAATATGATGAC CGATTGATGAAAGCAGCAGAAAGGGGGGATGTAGAAAAAGTGACCTCAATCCTTGCTAAAAAGGGGGTC AATCCAGGCAAACTAGATGTGGAAGGCAGATCTGTCTTCCATGTTGTGACCTCAAAGGGGAATCTTGAG TGTTTGAATGCCATCCTTATACATGGAGTTGATATTACAACCAGTGACACTGCAGGGAGAAATGCTCTT CACCTGGCTGCTAAGTATGGACATGCATTGTGCCTACAAAAACTTCTACAGTACAATTGTCCCACTGAG CATGCAGACCTGCAGGGAAGAACTGCACTTCACGATGCCGCAATGGCAGATTGTCCTTCTAGCATACAG CTGCTTTGTGACCATGGGGCCTCTGTGAATGCCAAAGATGTAGACGGGCGGACACCACTTGTTCTGGCT ACTCAGATGAGTAGGCCAACAATATGTCAACTGCTGATAGATAGAGGAGCGGATGTTAATTCCAGAGAC AAACAAAACAGAACTGCCCTCATGCTAGGTTGCGAATATGGTTGCAGAGATGCAGTAGAAGTCTTAATT AAAAATGGTGCTGATATAAGCTTGCTGGATGCGCTTGGCCATGATAGTTCTTACTATGCAAGAATTGGT GACAATCTGGACATTCTAACCTTGTTGAAGACTGCATCGGAAAATACCAACAAAGGGAGAGAACTTTGG AAGAAAGGGCCATCTTTGCAACAGCGAAATTTGACACACATGCAAGATGAAGTAAATGTGAAGTCACAT CAGAGGGAGCATCAAAATATTCAGGATTTGGAGATTGAAAATGAAGATTTGAAAGAGAGGTTGAGAAAA ATTCAGCAAGAACAAAGAATACTTTTGGATAAAGTCAATGGTTTACAGTTACAGCTGAATGAGGAAGTT ATGGTTGCTGATGATCTGGAAAGCGAGAGAGAAAAGCTGAAGTCCCTTTTGGCAGCTAAAGAAAAGCAA CATGAAGAAAGCTTAAGGACTATTGAGGCTCTGAAAAATAGATTTAAATATTTTGAGAGTGATCATTTA GGATCAGGAAGTCATTTCAGTAACCGAAAAGAAGATATGCTTCTTAAACAAGGTCAGATGTATATGGCA GACTCACAGTGTACTTCCCCAGGTATACCAGCCCATATGCAAAGCAGATCTATGTTAAGACCTCTGGAA CTATCTTTACCCAGTCAAACGTCATACTCTGAAAATGAAATTTTAAAGAAAGAGTTAGAAGCAATGCGA ACTTTCTGTGAGTCAGCAAAACAAGACCGACTGAAGCTCCAAAATGAACTGGCACACAAAGTGGCAGAA TGCAAAGCTTTAGCATTAGAATGTGAAAGGGTCAAGGAGGATTCAGATGAACAGATAAAGCAATTAGAA GATGCATTAAAAGATGTGCAGAAGAGGATGTATGAGTCAGAAGGTAAAGTTAAACAAATGCAGACCCAT TTTCTTGCCCTTAAAGAACACTTAACAAGTGAAGCAGCCTCAGGGAATCACAGACTAACCGAGGAACTG AAGGATCAGTTGAAAGACTTGAAAGTAAAATATGAAGGTGCTTCAGCAGAAGTGGGGAAATTAAGAAAC CAAATCAAACAAAATGAGATGATAGTAGAAGAGTTTAAGAGGGATGAAGGCAAGCTGATAGAAGAAAAT AAGCGATTACAGAAGGAACTTAGTATGTGTGAAATGGAGCGAGAGAAGAAAGGAAGAAAGGTCACAGAG ATGGAAGGCCAGGCAAAAGAATTGTCAGCGAAGTTGGCCCTTTCCATTCCAGCTGAAAAATTTGAAAAC ATGAAGAGCTCATTATCAAATGAAGTGAATGAGAAAGCAAAAAAATTAGTAGAAATGGAAAGAGAACAT GAAAAATCACTTAGTGAAATTAGACAGTTAAAGAGAGAACTTGAGAATGTTAAGGCCAAGCTTGCTCAG CACGTCAAACCAGAGGAACATGAACAGGTTAAGAGCAGATTAGAACAGAAATCAGGAGAACTTGGGAAG AAGATCACTGAGTTAACATTGAAAAATCAGACACTACAAAAGGAAATTGAAAAAGTTTATTTGGATAAT AAGCTCCTCAAGGAGCAAGCACATAACTTAACAATTGAAATGAAAAATCATTATGTTCCTTTAAAAGTA AGTGAAGACATGAAAAAGTCACATGATGCAATTATTGATGATCTTAATAGAAAGCTTTTAGATGTAACA CAAAAATATACAGAAAAGAAGTTGGAAATGGAGAAATTGCTACTGGAAAATGACAGCTTAAGTAAGGAT GTAAGCCGCCTAGAAACTGTGTTTGTACCTCCTGAGAAACATGAAAAAGAGATAATAGCTCTGAAATCC AATATTGTTGAACTTAAGAAACAGCTGTCTGAACTTAAGAAAAAATGTGGTGAAGACCAGGAGAAAATA CACGCTCTCACATCTGAAAACACTAACTTGAAGAAGATGATGAGTAATCAGTATGTGCCAGTTAAAACC CATGAAGAGGTTAAAATGACACTGAATGACACGTTAGCCAAAACTAACAGAGAATTATTAGATGTGAAG AAAAAATTTGAAGATATAAATCAGGAATTTGTAAAAATAAAAGATAAGAATGAAATATTAAAAAGAAAC CTGGAAAACACTCAGAACCAAATAAAAGCTGAGTACATCAGCCTGGCAGAGCACGAGGCAAAGATGAGC TCGCTAAGTCAGAGCATGAGAAAGGTGCAGGATAGTAATGCTGAAATCTTGGCCAACTACAGAAAAGGC CAAGAAGAGATTGTGACACTGCATGCCGAAATTAAAGCCCAGAAGAAGGAGCTCGACACAATACAAGAA TGCATTAAGGTAAAATACGCCCCAATTGTCAGCTTTGAGGAGTGCGAGAGAAAATTTAAAGCAACAGAG AAAGAACTAAAAGACCAGTTATCAGAGCAGACACAAAAGTATAGTGTCAGTGAAGAAGAAGTCAAGAAA AACAAGCAAGAGAATGACAAGTTAAAGAAGGAGATTTTTACCCTTCAGAAAGATTTGAGAGATAAGACA GTTCTCATTGAGAAGTCTCATGAAATGGAAAGAGCATTAAGCAGAAAAACAGACGAGCTAAACAAACAG TTAAAAGACTTGTCACAGAAATACACGGAAGTAAAGAATGTGAAAGAGAAGCTAGTAGAAGAAAATGCC AAACAGACTTCTGAGATACTTGCAGTGCAAAATCTTTTGCAAAAACAACATGTTCCATTGGAACAGGTT GAGGCTCTGAAAAAATCTCTTAATGGCACAATTGAAAATCTAAAGGAAGAACTGAAGAGTATGCAAAGG TGTTACGAGAAAGAGCAGCAGACAGTGACCAAACTGCATCAATTGTTGGAGAATCAAAAGAACTCTTCT GTACCCCTGGCAGAGCATTTGCAGATTAAAGAAGCATTTGAGAAAGAAGTTGGAATCATAAAAGCCAGC TTGAGAGAAAAGGAAGAAGAAAGCCAAAACAAAATGGAAGAAGTCTCCAAACTTCAGTCGGAGGTTCAG AATACTAAACAAGCATTAAAAAAATTAGAGACTAGAGAGGTAGTTGACTTGTCTAAATATAAAGCAACA AAAAGTGATTTGGAGACACAGATTTCTAGCTTAAATGAAAAATTGGCCAATCTGAATAGAAAGTATGAG GAAGTATGTGAGGAAGTTTTGCATGCCAAAAAGAAGGAAATATCTGCAAAAGATGAGAAGGAATTACTG CATTTCAGCATTGAGCAAGAAATTAAGGATCAGAAGGAACGATGTGATAAGTCCTTAACAACAATCACA GAGTTACAAAGAAGAATACAAGAATCTGCTAAACAAATAGAAGCAAAAGATAATAAGATAACTGAACTG CTTAATGATGTGGAAAGATTAAAACAGGCACTCAATGGCCTTTCCCAACTCACCTACACAAGTGGGAAC CCCACCAAGAGGCAGAGCCAGCTGATTGACACTCTGCAGCACCAAGTGAAATCTCTGGAGCAACAGCTG GCCGATGCTGACAGACAGCACCAAGAAGTAATTGCAATTTATCGGACACACCTTCTTAGTGCTGCACAG GGTCACATGGATGAAGATGTTCAGGAGGCTCTGCTCCAGATCATACAAATGCGGCAGGGGCTTGTGTGC TAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
Restriction Sites | SgfI-MluI |
ACCN | NM_001008224 |
Insert Size | 4212 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001008224.1 |
RefSeq Size | 7096 bp |
RefSeq ORF | 4212 bp |
Locus ID | 55075 |
UniProt ID | Q9BZF9 |
MW | 161.5 kDa |
Gene Summary | This gene encodes a protein that contains ankyrin repeats and coiled coil domains and likely plays a role in apoptosis. Studies in rodents have implicated the encoded protein in the stimulation of apoptosis and the regulation of mammary gland involution, in which the mammary gland returns to its pre-pregnant state. This protein has also been proposed to negatively regulate apoptosis based on experiments in human cell lines in which the protein was shown to interact with PRKC apoptosis WT1 regulator protein, also known as PAR-4, and inhibit translocation of the PAR-4 receptor. Autoantibodies to this protein have been identified in human patients with panuveitis and Graves' disease. Differential expression of this gene has been observed in various human cancers. [provided by RefSeq, May 2017] Transcript Variant: This variant (2) has a longer and alternate 5' exon, as compared to variant 1. The encoded isoform 2 has a shorter and distinct N-terminus, as compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC222247 | UACA (Myc-DDK-tagged)-Human uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA), transcript variant 2 |
CNY 9,600.00 |
|
RC222247L3 | Lenti-ORF clone of UACA (Myc-DDK-tagged)-Human uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA), transcript variant 2 |
CNY 15,870.00 |
|
RC222247L4 | Lenti-ORF clone of UACA (mGFP-tagged)-Human uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA), transcript variant 2 |
CNY 15,870.00 |
|
RG222247 | UACA (tGFP-tagged) - Human uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA), transcript variant 2 |
CNY 15,390.00 |