LOK (STK10) (NM_005990) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC209827L4V
- LentiORF®
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Lenti ORF particles, STK10 (mGFP-tagged)-Human serine/threonine kinase 10 (STK10), 200ul, >10^7 TU/mL
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CNY 9,975.00
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Specifications
Product Data | |
Product Name | LOK (STK10) (NM_005990) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | LOK; PRO2729 |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_005990 |
ORF Size | 2904 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC209827).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_005990.2, NP_005981.2 |
RefSeq Size | 6039 bp |
RefSeq ORF | 2907 bp |
Locus ID | 6793 |
Domains | pkinase, TyrKc, S_TKc |
Protein Families | Druggable Genome, Protein Kinase |
MW | 112.1 kDa |
Gene Summary | This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway. [provided by RefSeq, Jul 2008] |
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