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Calpain 10 (CAPN10) (NM_023083) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC202556L3V
- LentiORF®
-
Lenti ORF particles, CAPN10 (Myc-DDK tagged) - Human calpain 10 (CAPN10), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 8,930.00
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Specifications
| Product Data | |
| Product Name | Calpain 10 (CAPN10) (NM_023083) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | CANP10; NIDDM1 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_023083 |
| ORF Size | 2016 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC202556).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_023083.2, NP_075571.1 |
| RefSeq Size | 2662 bp |
| RefSeq ORF | 2019 bp |
| Locus ID | 11132 |
| Protein Families | Druggable Genome, Protease |
| MW | 74.9 kDa |
| Gene Summary | Calpains represent a ubiquitous, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation; domain II, the protease domain; domain III, a linker domain of unknown function; and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM), and is located within the NIDDM1 region. Multiple alternative transcript variants have been described for this gene. [provided by RefSeq, Sep 2010] |
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