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Bmp3 (NM_173404) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR223213L3V
- LentiORF®
-
Lenti ORF particles, Bmp3 (Myc-DDK-tagged) - Mouse bone morphogenetic protein 3 (Bmp3), 200ul, >10^7 TU/mL
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CNY 9,120.00
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规格
| Cited in 1 publication. |
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经常一起买 (2)
Specifications
| Product Data | |
| Product Name | Bmp3 (NM_173404) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 9530029I04Rik; D630004D15R |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_173404 |
| ORF Size | 1407 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR223213).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_173404.3, NP_775580.1 |
| RefSeq Size | 3112 bp |
| RefSeq ORF | 1407 bp |
| Locus ID | 110075 |
| Gene Summary | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein suppresses osteoblast differentiation, and negatively regulates bone density, by modulating TGF-beta receptor availability to other ligands. Homozygous knockout mice for this gene exhibit increased bone density and volume, while overexpression of this gene in a transgenic mouse causes bone defects resulting in spontaneous rib fractures. This gene encodes distinct protein isoforms that may be similarly proteolytically processed. [provided by RefSeq, Jul 2016] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Methylated Bone Morphogenetic Protein 3 (BMP3) Gene: Evaluation of Tumor Suppressor Function and Biomarker Potential in Biliary Cancer
,null,
Journal of molecular biomarkers & diagnosis
,PubMed ID 25077038
[Bmp3]
|
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