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Bmp3 (NM_173404) Mouse Untagged Clone
CAT＃: MC216355
Bmp3 (untagged) - Mouse bone morphogenetic protein 3 (Bmp3), (10ug)
CNY 6,080.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 9530029I04Rik; D630004D15R |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC216355 representing NM_173404
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCCGGGGCGCGCGGGCTGCTCTGTCTATGGCTAGGTTACTTCTGCCTGAACCTGGCACAGGGACAGA GACCAAACTTGCACCTCCCGGGACTCCGTGAGACTGAGCCAAGCGACCGCGCGACAGGTGGTAGCCCGAG TCCGGACCTGAGGCCGCACGACAAGGTGTCGGAGCATATGCTGTGGCTCTATGACAGGTACAGCGGCAGC AGTAGAGTCCAGGCTACCCGGACACCGGGCTCGCAGCTCCCGGGTCCTCAGCCCCTGCGCGGTGGTAACA CGGTCCGCAGCTTCAGAGCCGCAGCCGCAGGAACTCCTCAAACGAAGGGGTTACACACCTTCAATCTGAC TTCTCTAACCAAGTCGGAGAACATTTTGTCAGCCACACTGTATTTCTACGTTGGAGAATTAGTGAACATC AGCTTGAGCTGTCCAGAACCCCAAGGATGCTCCCATCACACTCAGAGACAACACATCCAGATAGACCTCT CTGCATGGATCCTCAAATCCAACCAAAGCCAGCTCTTGGGTCATCTGTCTGTAGATGTGGTCAGACCTTA TAGAGACAGCGTGTCTTGGCTGTCAAAAGACATCACTCAGCTCTTAAGAAAGGCCAAGCAAAATGAAGAG TTTCTCATAGGGTTTAACATTACCTCCAGAGCACACGAGCTACCCAAGAGGATGCTGTTTTTCCCGGAAC CTTATATCTTGGTATACGCCAACGATGCTGCCATTTCTGAGCCAGAAAGCGTGGTATCCAGCTTACAGAG ACACCGAGATTTCACAGCGGGAACTGGGCCCAGACTGGATAGCCACGTCAGAGAAGCCCTCTCGGTTGAG AGGAGGAAGAAGCGCTCTACTGGGATCTTGCTGCCCTTGCAGAACAATGAGCTACCTGGGGCAGAGTATC AGTACAAGGAGGAGGGAGCGTGGGAGGAGAGAAAGCCTTATAAGAGCCTTCAGACTCAGCCCCCTGAGAA GAGTAGGAACAAAAAGAAACAGAGGAAAGGGTCCCATCAGAAGGGACAGACGCTGCAATTTGATGAGCAG ACCCTGAAGAAGGCAAGGCGAAAGCAGTGGGTCGAACCTCGGAACTGTGCCAGGAGGTACCTTAAAGTGG ACTTTGCTGATATCGGCTGGAGCGAATGGATTATCTCTCCCAAGTCATTTGATGCTTTCTACTGCTCTGG AGCCTGCCAGTTCCCCATGCCAAAGTCTTTGAAACCATCAAATCACGCCACCATCCAGAGCATAGTGCGA GCGGTGGGGGTCGTCTCCGGGATTCCCGAGCCTTGCTGTGTGCCGGAAAAGATGTCCTCACTCAGCATCT TGTTCTTTGATGAAAACAAGAATGTAGTGCTCAAAGTCTACCCTAACATGACAGTCGACTCCTGTGCTTG TAGATAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_173404 |
| Insert Size | 1407 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_173404.5, NP_775580.1 |
| RefSeq Size | 6229 bp |
| RefSeq ORF | 1407 bp |
| Locus ID | 110075 |
| UniProt ID | Q8BHE5 |
| Gene Summary | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein suppresses osteoblast differentiation, and negatively regulates bone density, by modulating TGF-beta receptor availability to other ligands. Homozygous knockout mice for this gene exhibit increased bone density and volume, while overexpression of this gene in a transgenic mouse causes bone defects resulting in spontaneous rib fractures. This gene encodes distinct protein isoforms that may be similarly proteolytically processed. [provided by RefSeq, Jul 2016] Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region, which results in a frameshift, compared to variant 1. The encoded isoform (2) has a distinct, shorter C-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG223213 | Bmp3 (tGFP-tagged) - Mouse bone morphogenetic protein 3 (Bmp3), (10ug) |
CNY 3,710.00 |
|
| MR223213 | Bmp3 (Myc-DDK-tagged) - Mouse bone morphogenetic protein 3 (Bmp3) |
CNY 3,656.00 |
|
| MR223213L3 | Lenti ORF clone of Bmp3 (Myc-DDK-tagged) - Mouse bone morphogenetic protein 3 (Bmp3) |
CNY 5,230.00 |
|
| MR223213L4 | Lenti ORF clone of Bmp3 (mGFP-tagged) - Mouse bone morphogenetic protein 3 (Bmp3) |
CNY 5,230.00 |
