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E2f6 (BC019166) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR202901L4V
- LentiORF®
-
Lenti ORF particles, E2f6 (GFP-tagged) - Mouse E2F transcription factor 6 (cDNA clone MGC:29087 IMAGE:4236246), 200ul, >10^7 TU/mL
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CN¥ 11,115.00
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Specifications
| Product Data | |
| Product Name | E2f6 (BC019166) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | EMA, E2F6b |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | BC019166 |
| ORF Size | 711 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR202901).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | BC019166.1 |
| RefSeq Size | 2506 bp |
| RefSeq ORF | 713 bp |
| Locus ID | 50496 |
| Gene Summary | Inhibitor of E2F-dependent transcription. Binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Has a preference for the 5'-TTTCCCGC-3' E2F recognition site. E2F6 lacks the transcriptional activation and pocket protein binding domains. Appears to regulate a subset of E2F-dependent genes whose products are required for entry into the cell cycle but not for normal cell cycle progression. May silence expression via the recruitment of a chromatin remodeling complex containing histone H3-K9 methyltransferase activity. Overexpression delays the exit of cells from the S-phase (By similarity).[UniProtKB/Swiss-Prot Function] |
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