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BBS10 (NM_024685) Human Untagged Clone
CAT＃: SC318204
BBS10 (untagged)-Human Bardet-Biedl syndrome 10 (BBS10)
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | C12orf58 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC318204 representing NM_024685.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGTTAAGTTCTATGGCCGCTGCAGGGTCTGTGAAGGCGGCGTTGCAGGTGGCCGAGGTGCTGGAAGCC ATCGTGAGCTGCTGCGTGGGGCCCGAGGGACGGCAAGTTTTGTGTACGAAGCCCACTGGCGAGGTGCTT CTCAGCCGGAATGGAGGCCGCCTCCTGGAGGCGCTACACTTAGAGCATCCCATAGCCAGGATGATAGTG GACTGTGTTTCCAGTCATCTCAAAAAAACAGGAGATGGTGCAAAAACATTTATTATCTTTCTTTGCCAT TTGCTTAGAGGACTTCATGCAATCACAGACAGAGAAAAGGATCCTTTGATGTGTGAAAACATTCAAACC CATGGAAGGCATTGGAAAAATTGTTCTCGGTGGAAATTTATTTCCCAGGCTCTCCTAACGTTTCAGACA CAAATATTAGACGGTATTATGGACCAGTACCTAAGTAGACACTTTTTGTCTATCTTTTCGTCTGCTAAA GAGAGAACATTGTGTAGGAGCTCTTTAGAGTTGCTCTTAGAAGCATACTTTTGTGGAAGAGTGGGAAGA AATAATCATAAATTTATTTCACAGTTGATGTGTGACTACTTTTTCAAGTGTATGACTTGTAAAAGTGGG ATTGGTGTATTTGAGTTAGTGGATGACCATTTTGTAGAGTTGAATGTTGGTGTCACTGGCCTTCCTGTT TCAGATTCCAGGATCATAGCTGGTCTTGTGCTTCAGAAAGATTTTTCTGTGTACCGCCCAGCAGATGGT GACATGCGAATGGTGATAGTAACAGAAACCATTCAGCCTCTTTTTTCCACTTCTGGATCAGAGTTTATT CTAAATTCAGAAGCACAGTTTCAGACATCTCAATTTTGGATTATGGAAAAGACAAAAGCAATAATGAAA CATCTACATAGTCAGAATGTAAAATTGCTCATATCTAGTGTGAAACAACCAGATTTAGTTAGTTATTAT GCAGGGGTGAATGGCATATCAGTGGTTGAGTGTTTATCATCAGAAGAAGTTTCTCTTATCCGGAGGATC ATTGGTCTTTCTCCATTTGTACCACCACAGGCCTTTTCGCAGTGTGAAATACCTAACACTGCTTTGGTG AAATTTTGTAAACCTCTTATCCTTAGATCCAAAAGATATGTTCATCTAGGCTTGATAAGCACATGTGCA TTTATACCACACTCTATAGTTCTTTGTGGACCAGTGCATGGTCTCATTGAACAACATGAGGATGCTTTA CATGGAGCACTTAAAATGCTTCGGCAATTATTTAAAGACCTTGATCTAAATTACATGACACAAACCAAT GACCAAAATGGCACTTCAAGTCTTTTTATTTATAAGAACAGTGGAGAAAGTTATCAAGCACCAGATCCT GGTAATGGCTCAATACAAAGGCCTTATCAGGACACAGTTGCAGAGAACAAAGATGCATTGGAAAAAACT CAAACATATTTAAAAGTACATTCTAATTTGGTAATTCCAGATGTAGAATTAGAAACATATATTCCGTAT TCAACCCCCACACTGACACCAACAGATACATTCCAAACAGTTGAAACGCTGACATGTTTGTCTTTGGAA AGAAACAGGCTAACTGATTATTATGAACCATTACTCAAGAACAATTCCACTGCTTATTCAACAAGGGGA AATAGAATAGAAATTTCTTACGAAAATTTACAGGTCACAAATATTACTAGAAAGGGAAGCATGTTACCA GTGAGCTGTAAGTTACCGAATATGGGTACTTCCCAGAGTTACCTTTCCTCATCTATGCCAGCTGGTTGT GTTTTGCCAGTAGGTGGTAATTTTGAGATCTTGTTACATTACTATCTTCTCAATTATGCCAAAAAATGC CATCAATCAGAAGAAACCATGGTTAGTATGATAATAGCTAATGCACTTTTAGGCATTCCCAAAGTCCTT TATAAATCTAAAACAGGAAAGTACAGCTTTCCACATACATATATAAGAGCTGTCCATGCACTGCAAACC AATCAACCCTTGGTAAGCAGTCAGACAGGTTTGGAATCAGTAATGGGTAAATACCAGCTACTAACTTCA GTTCTTCAGTGTTTGACAAAAATATTAACCATTGACATGGTAATCACTGTTAAGAGACACCCTCAGAAA GTTCACAATCAAGATTCAGAAGATGAACTATAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_024685 |
| Insert Size | 2172 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_024685.3 |
| RefSeq Size | 3583 bp |
| RefSeq ORF | 2172 bp |
| Locus ID | 79738 |
| UniProt ID | Q8TAM1 |
| MW | 80.8 kDa |
| Gene Summary | This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by progressive retinal degeneration, obesity, polydactyly, renal malformation and cognitive disability. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene is likely not a ciliary protein but rather has distant sequence homology to type II chaperonins. As a molecular chaperone, this protein may affect the folding or stability of other ciliary or basal body proteins. Inhibition of this protein's expression impairs ciliogenesis in preadipocytes. Mutations in this gene cause Bardet-Biedl syndrome type 10. [provided by RefSeq, Jan 2010] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC205501 | BBS10 (Myc-DDK-tagged)-Human Bardet-Biedl syndrome 10 (BBS10) |
CNY 5,296.00 |
|
| RC205501L3 | Lenti ORF clone of Human Bardet-Biedl syndrome 10 (BBS10), Myc-DDK-tagged |
CNY 7,700.00 |
|
| RC205501L4 | Lenti ORF clone of Human Bardet-Biedl syndrome 10 (BBS10), mGFP tagged |
CNY 7,700.00 |
|
| RG205501 | BBS10 (tGFP-tagged) - Human Bardet-Biedl syndrome 10 (BBS10) |
CNY 6,896.00 |
|
| SC108312 | BBS10 (untagged)-Human Bardet-Biedl syndrome 10 (BBS10) |
CNY 7,220.00 |
