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BBS10 (NM_024685) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC205501L4V
- LentiORF®
-
Lenti ORF particles, BBS10 (mGFP-tagged) - Human Bardet-Biedl syndrome 10 (BBS10), 200ul, >10^7 TU/mL
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CNY 9,975.00
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规格
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Specifications
| Product Data | |
| Product Name | BBS10 (NM_024685) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | C12orf58 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_024685 |
| ORF Size | 2169 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC205501).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_024685.3, NP_078961.3 |
| RefSeq Size | 3583 bp |
| RefSeq ORF | 2172 bp |
| Locus ID | 79738 |
| MW | 80.8 kDa |
| Gene Summary | This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by progressive retinal degeneration, obesity, polydactyly, renal malformation and cognitive disability. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene is likely not a ciliary protein but rather has distant sequence homology to type II chaperonins. As a molecular chaperone, this protein may affect the folding or stability of other ciliary or basal body proteins. Inhibition of this protein's expression impairs ciliogenesis in preadipocytes. Mutations in this gene cause Bardet-Biedl syndrome type 10. [provided by RefSeq, Jan 2010] |
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