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UBR1 (NM_174916) Human Untagged Clone
CAT＃: SC309224
UBR1 (untagged)-Human ubiquitin protein ligase E3 component n-recognin 1 (UBR1)
CNY 26,790.00
货期*
4周
规格
Product images
经常一起买 (3)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | JBS |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC309224 representing NM_174916.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGCGGACGAGGAGGCTGGAGGTACTGAGAGGATGGAAATCAGCGCGGAGTTACCCCAGACCCCTCAG CGTCTGGCATCTTGGTGGGATCAGCAAGTTGATTTTTATACTGCTTTCTTGCATCATTTGGCACAATTG GTGCCAGAAATTTACTTTGCTGAAATGGACCCAGACTTGGAAAAGCAGGAGGAAAGTGTACAAATGTCA ATATTCACTCCACTGGAATGGTACTTATTTGGAGAAGATCCAGATATTTGCTTAGAGAAATTGAAGCAC AGTGGAGCATTTCAGCTTTGTGGGAGGGTTTTCAAAAGTGGAGAGACAACCTATTCTTGCAGGGATTGT GCAATTGATCCAACATGTGTACTCTGTATGGACTGCTTCCAGGACAGTGTTCATAAAAATCATCGTTAC AAGATGCATACTTCTACTGGAGGAGGGTTCTGTGACTGTGGAGACACAGAGGCATGGAAAACTGGCCCT TTTTGTGTAAATCATGAACCTGGAAGAGCAGGTACTATAAAAGAGAATTCACGCTGTCCGTTGAATGAA GAGGTAATTGTCCAAGCCAGGAAAATATTTCCTTCAGTGATAAAATATGTCGTAGAAATGACTATATGG GAAGAGGAAAAAGAACTGCCTCCTGAACTCCAGATAAGGGAGAAAAATGAAAGATACTATTGTGTCCTT TTCAATGATGAACACCATTCATATGACCACGTCATATACAGCCTACAAAGAGCTCTTGACTGTGAGCTC GCAGAGGCCCAGTTGCATACCACTGCCATTGACAAAGAGGGTCGTCGGGCTGTTAAAGCGGGAGCTTAT GCTGCTTGCCAGGAAGCAAAGGAAGATATAAAGAGTCATTCAGAAAATGTCTCTCAACATCCACTTCAT GTAGAAGTATTACACTCAGAGATTATGGCTCATCAGAAATTTGCTTTGCGTCTTGGTTCCTGGATGAAC AAAATTATGAGCTATTCAAGTGACTTTAGGCAGATCTTTTGCCAAGCATGCCTTAGAGAAGAACCTGAC TCGGAGAATCCCTGTCTCATAAGCAGGTTAATGCTTTGGGATGCAAAGCTTTATAAAGGTGCCCGTAAG ATCCTTCATGAATTGATCTTCAGCAGTTTTTTTATGGAGATGGAATACAAAAAACTCTTTGCTATGGAA TTTGTGAAGTATTATAAACAACTGCAGAAAGAATATATCAGTGATGATCATGACAGAAGTATCTCTATA ACTGCACTTTCAGTTCAGATGTTTACTGTTCCTACTCTGGCTCGACATCTTATTGAAGAGCAGAATGTT ATCTCTGTCATTACTGAAACTCTGCTAGAAGTTTTACCTGAGTACTTGGACAGGAACAATAAATTCAAC TTCCAGGGTTATAGCCAGGACAAATTGGGAAGAGTATATGCAGTAATATGTGACCTAAAGTATATCCTG ATCAGCAAACCCACAATATGGACAGAAAGATTAAGAATGCAGTTCCTTGAAGGTTTTCGATCTTTTTTG AAGATTCTTACCTGTATGCAGGGAATGGAAGAAATCCGAAGACAGGTTGGGCAACACATTGAAGTGGAT CCTGATTGGGAGGCTGCCATTGCTATACAGATGCAATTGAAGAATATTTTACTCATGTTCCAAGAGTGG TGTGCTTGTGATGAAGAACTCTTACTTGTGGCTTATAAAGAATGTCACAAAGCTGTGATGAGGTGCAGT ACCAGTTTCATATCTAGTAGCAAGACAGTAGTACAATCGTGTGGACATAGTTTGGAAACAAAGTCCTAC AGAGTATCTGAGGATCTTGTAAGCATACATCTGCCACTCTCTAGGACCCTTGCTGGTCTTCATGTACGT TTAAGCAGGCTGGGTGCTGTTTCAAGACTGCATGAATTTGTGTCTTTTGAGGACTTTCAAGTAGAGGTA CTAGTGGAATATCCTTTACGTTGTCTGGTGTTGGTTGCCCAGGTTGTTGCTGAGATGTGGCGAAGAAAT GGACTGTCTCTTATTAGCCAGGTGTTTTATTACCAAGATGTTAAGTGCAGAGAAGAAATGTATGATAAA GATATCATCATGCTTCAGATTGGTGCATCTTTAATGGATCCCAATAAGTTCTTGTTACTGGTACTTCAG AGGTATGAACTTGCCGAGGCTTTTAACAAGACCATATCTACAAAAGACCAGGATTTGATTAAACAATAT AATACACTAATAGAAGAAATGCTTCAGGTCCTCATCTATATTGTGGGTGAGCGTTATGTACCTGGAGTG GGAAATGTGACCAAAGAAGAGGTCACAATGAGAGAAATCATTCACTTGCTTTGCATTGAACCCATGCCA CACAGTGCCATTGCCAAAAATTTACCTGAGAATGAAAATAATGAAACTGGCTTAGAGAATGTCATAAAC AAAGTGGCCACATTTAAGAAACCAGGTGTATCAGGCCATGGAGTTTATGAACTAAAAGATGAATCACTG AAAGACTTCAATATGTACTTTTATCATTACTCCAAAACCCAGCATAGCAAGGCTGAACATATGCAGAAG AAAAGGAGAAAACAAGAAAACAAAGATGAAGCATTGCCGCCACCACCACCTCCTGAATTCTGCCCTGCT TTCAGCAAAGTGATTAACCTTCTCAACTGTGATATCATGATGTACATTCTCAGGACCGTATTTGAGCGG GCAATAGACACAGATTCTAACTTGTGGACCGAAGGGATGCTCCAAATGGCTTTTCATATTCTGGCATTG GGTTTACTAGAAGAGAAGCAACAGCTTCAAAAAGCTCCTGAAGAAGAAGTAACATTTGACTTTTATCAT AAGGCTTCAAGATTGGGAAGTTCAGCCATGAATATACAAATGCTTTTGGAAAAACTCAAAGGAATTCCC CAGTTAGAAGGCCAGAAGGACATGATAACGTGGATACTTCAGATGTTTGACACAGTGAAGCGATTAAGA GAAAAATCTTGTTTAATTGTAGCAACCACATCAGGATCGGAATCTATTAAGAATGATGAGATTACTCAT GATAAAGAAAAAGCAGAACGAAAAAGAAAAGCTGAAGCTGCTAGGCTACATCGCCAGAAGATCATGGCT CAGATGTCTGCCTTACAGAAAAACTTCATTGAAACTCATAAACTCATGTATGACAATACATCAGAAATG CCTGGGAAAGAAGATTCCATTATGGAGGAAGAGAGCACCCCAGCAGTCAGTGACTACTCTAGAATTGCT TTGGGTCCTAAACGGGGTCCATCTGTTACTGAAAAGGAGGTGCTGACGTGCATCCTTTGCCAAGAAGAA CAGGAGGTGAAAATAGAAAATAATGCCATGGTATTATCGGCCTGTGTCCAGAAATCTACTGCCTTAACC CAGCACAGGGGAAAACCCATAGAACTCTCAGGAGAAGCCCTAGACCCACTTTTCATGGATCCAGACTTG GCATATGGAACTTATACAGGAAGCTGTGGTCATGTAATGCACGCAGTGTGCTGGCAGAAGTATTTTGAA GCTGTACAGCTGAGCTCTCAGCAGCGCATTCATGTTGACCTTTTTGACTTGGAAAGTGGAGAATATCTT TGCCCTCTTTGCAAATCTCTGTGCAATACTGTGATCCCCATTATTCCTTTGCAACCTCAAAAGATAAAC AGTGAGAATGCAGATGCTCTTGCTCAACTTTTGACCCTGGCACGGTGGATACAGACTGTTCTGGCCAGA ATATCAGGTTATAATATAAGACATGCTAAAGGAGAAAACCCAATTCCTATTTTCTTTAATCAAGGAATG GGAGATTCTACTTTGGAGTTCCATTCCATCCTGAGTTTTGGCGTTGAGTCTTCGATTAAATATTCAAAT AGCATCAAGGAAATGGTTATTCTCTTTGCCACAACAATTTATAGAATTGGATTGAAAGTGCCACCTGAT GAAAGGGATCCTCGAGTCCCCATGCTGACCTGGAGCACCTGCGCTTTCACTATCCAGGCAATTGAAAAT CTATTGGGAGATGAAGGAAAACCTCTGTTTGGAGCACTTCAAAATAGGCAGCATAATGGTCTGAAAGCA TTAATGCAGTTTGCAGTTGCACAGAGGATTACCTGTCCTCAGGTCCTGATACAGAAACATCTGGTTCGT CTTCTATCAGTTGTTCTTCCTAACATAAAATCAGAAGATACACCATGCCTTCTGTCTATAGATCTGTTT CATGTTTTGGTGGGTGCTGTGTTAGCATTCCCATCCTTGTATTGGGATGACCCTGTTGATCTGCAGCCT TCTTCAGTTAGTTCTTCCTATAACCACCTTTATCTCTTCCATTTGATCACCATGGCACACATGCTTCAG ATACTACTTACAGTAGACACAGGCCTACCCCTTGCTCAGGTTCAAGAAGACAGTGAAGAGGCTCATTCC GCATCTTCTTTCTTTGCAGAAATTTCTCAATATACAAGTGGCTCCATTGGGTGTGATATTCCTGGCTGG TATTTGTGGGTCTCACTGAAGAATGGCATCACCCCTTATCTTCGCTGTGCTGCATTGTTTTTCCACTAT TTACTTGGGGTAACTCCGCCTGAGGAACTGCATACCAATTCTGCAGAAGGAGAGTACAGTGCACTCTGT AGCTATCTATCTTTACCTACAAATTTGTTCCTGCTCTTCCAGGAATATTGGGATACTGTAAGGCCCTTG CTCCAGAGGTGGTGTGCAGATCCTGCCTTACTAAACTGTTTGAAGCAAAAAAACACCGTGGTCAGGTAC CCTAGAAAAAGAAATAGTTTGATAGAGCTTCCTGATGACTATAGCTGCCTCCTGAATCAAGCTTCTCAT TTCAGGTGCCCACGGTCTGCAGATGATGAGCGAAAGCATCCTGTCCTCTGCCTTTTCTGTGGGGCTATA CTATGTTCTCAGAACATTTGCTGCCAGGAAATTGTGAACGGGGAAGAGGTTGGAGCTTGCATTTTTCAC GCACTTCACTGTGGAGCCGGAGTCTGCATTTTCCTAAAAATCAGAGAATGCCGAGTGGTCCTGGTTGAA GGTAAAGCCAGAGGCTGTGCCTATCCAGCTCCTTACTTGGATGAATATGGAGAAACAGACCCTGGCCTG AAGAGGGGCAACCCCCTTCATTTATCTCGTGAGCGGTATCGGAAGCTCCATTTGGTCTGGCAACAACAC TGCATTATAGAAGAGATTGCTAGGAGCCAAGAGACTAATCAGATGTTATTTGGATTCAACTGGCAGTTA CTGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_174916 |
| Insert Size | 5250 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_174916.2 |
| RefSeq Size | 7758 bp |
| RefSeq ORF | 5250 bp |
| Locus ID | 197131 |
| UniProt ID | Q8IWV7 |
| Protein Families | Druggable Genome |
| MW | 200.2 kDa |
| Gene Summary | The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome. [provided by RefSeq, Jul 2008] |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC219454 | UBR1 (Myc-DDK-tagged)-Human ubiquitin protein ligase E3 component n-recognin 1 (UBR1) |
CNY 17,632.00 |
|
| RC219454L1 | Lenti ORF clone of Human ubiquitin protein ligase E3 component n-recognin 1 (UBR1), Myc-DDK-tagged |
CNY 19,380.00 |
|
| RC219454L3 | Lenti ORF clone of Human ubiquitin protein ligase E3 component n-recognin 1 (UBR1), Myc-DDK-tagged |
CNY 19,380.00 |
|
| RG219454 | UBR1 (tGFP-tagged) - Human ubiquitin protein ligase E3 component n-recognin 1 (UBR1) |
CNY 19,190.00 |
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