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UBR1 (NM_174916) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC219454L3V
- LentiORF®
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Lenti ORF particles, UBR1 (Myc-DDK tagged) - Human ubiquitin protein ligase E3 component n-recognin 1 (UBR1), 200ul, >10^7 TU/mL
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CNY 21,660.00
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Specifications
| Product Data | |
| Product Name | UBR1 (NM_174916) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | JBS |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_174916 |
| ORF Size | 5247 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC219454).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_174916.2 |
| RefSeq Size | 7758 bp |
| RefSeq ORF | 5250 bp |
| Locus ID | 197131 |
| Protein Families | Druggable Genome |
| MW | 200 kDa |
| Gene Summary | The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome. [provided by RefSeq, Jul 2008] |
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