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CLCN1 (NM_000083) Human Untagged Clone
CAT＃: SC122070
CLCN1 (untagged)-Human chloride channel 1, skeletal muscle (CLCN1)
CNY 7,176.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CLC1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_000083 edited
AAGGACAGGGGCAAGCAGGCCAAGGCCTGGCCGGGGCTCGGGGGGAGGGAATATGGAGCA ATCCCGGTCACAGCAGCGTGGGGGTGAACAAAGCTGGTGGGGTAGTGACCCCCAGTACCA GTATATGCCCTTTGAACACTGCACCAGCTACGGACTGCCCTCTGAGAATGGGGGCCTCCA GCACAGGCTCCGGAAGGATGCAGGCCCCCGCCACAACGTCCACCCCACACAGATTTATGG CCATCACAAAGAACAATTCTCAGACAGGGAGCAGGACATAGGGATGCCCAAGAAGACAGG CTCCAGTTCTACCGTGGACAGCAAGGATGAGGATCACTATTCTAAATGTCAAGATTGTAT CCACCGCCTGGGACAGGTGGTGAGAAGAAAATTAGGGGAAGACTGGATCTTTCTGGTGCT TCTGGGACTGCTGATGGCTCTGGTCAGCTGGAGCATGGACTACGTCAGTGCCAAAAGCCT TCAGGCCTACAAGTGGTCCTACGCGCAGATGCAGCCCAGCCTTCCTCTGCAGTTCCTGGT CTGGGTCACCTTCCCACTAGTCCTCATCCTCTTCAGCGCCCTCTTCTGCCACCTCATCTC TCCCCAGGCTGTTGGCTCTGGAATCCCCGAAATGAAGACAATACTTCGTGGGGTTGTCCT GAAGGAATACCTCACAATGAAAGCCTTTGTGGCCAAGGTTGTCGCCCTGACTGCGGGCCT GGGCAGTGGCATCCCCGTGGGGAAAGAGGGCCCCTTCGTCCACATTGCCAGCATCTGTGC TGCTGTCCTCAGCAAATTCATGTCTGTGTTCTGCGGGGTATATGAGCAGCCATACTACTA CTCTGATATCCTGACGGTGGGCTGTGCTGTGGGAGTCGGCTGTTGTTTTGGGACACCACT TGGAGGAGTGCTATTTAGCATCGAGGTCACCTCCACCTACTTTGCTGTTCGGAACTACTG GAGAGGATTCTTTGCAGCCACGTTCAGCGCCTTTGTGTTTCGAGTGCTGGCAGTGTGGAA CAAGGATGCTGTCACCATCACTGCTCTGTTCAGAACCAATTTCCGAATGGATTTCCCCTT TGACCTGAAGGAACTACCAGCTTTTGCTGCCATCGGGATTTGCTGTGGGCTCCTGGGAGC TGTATTTGTGTATCTGCATCGCCAAGTCATGCTCGGTGTCCGAAAGCACAAGGCCCTCAG CCAGTTTCTTGCTAAGCACCGCCTGCTGTATCCTGGAATTGTTACCTTTGTCATTGCCTC ATTCACCTTCCCACCAGGAATGGGTCAATTCATGGCTGGAGAGTTGATGCCCCGCGAAGC CATCAGTACTTTGTTTGACAACAATACATGGGTGAAACACGCGGGTGATCCTGAGAGCCT GGGCCAGTCAGCTGTGTGGATTCACCCCCGGGTCAACGTTGTCATCATCATCTTTCTCTT CTTCGTCATGAAGTTCTGGATGTCCATCGTGGCCACCACTATGCCCATACCCTGCGGAGG CTTCATGCCTGTGTTTGTGCTAGGAGCTGCATTTGGAAGGCTGGTAGGAGAAATCATGGC CATGCTCTTTCCTGATGGTATTTTGTTTGATGACATCATCTACAAGATCCTACCTGGGGG CTATGCAGTAATTGGAGCAGCAGCGCTGACTGGTGCCGTTTCCCACACAGTCTCCACAGC TGTGATTTGCTTCGAATTAACGGGTCAGATTGCTCACATCCTGCCCATGATGGTGGCTGT TATCTTGGCCAACATGGTGGCCCAGAGCCTGCAGCCCTCTCTCTATGACAGCATCATCCA GGTCAAGAAGCTACCCTACTTGCCTGACCTTGGCTGGAACCAGCTCAGCAAATATACCAT CTTTGTTGAGGACATCATGGTACGTGATGTGAAGTTTGTTTCAGCTTCTTACACATATGG GGAGTTGCGAACCCTGCTCCAGACCACCACAGTCAAGACTTTACCACTGGTTGACTCAAA AGATTCAATGATCCTGCTGGGCTCGGTGGAGCGGTCGGAACTGCAGGCCCTCCTGCAGCG CCACCTGTGTCCTGAGCGCAGGCTGCGCGCAGCCCAAGAGATGGCGCGGAAGTTGTCGGA GCTGCCTTACGACGGGAAGGCGCGGCTGGCTGGGGAGGGGCTCCCCGGCGCGCCTCCAGG CCGGCCCGAGTCCTTCGCCTTTGTGGATGAGGATGAGGACGAAGATCTCTCTGGCAAGAG CGAGCTTCCTCCTTCCCTTGCTCTCCACCCCTCTACTACTGCCCCTCTGTCCCCAGAAGA GCCCAATGGGCCTCTGCCTGGCCACAAACAGCAGCCGGAAGCACCAGAGCCTGCAGGTCA AAGACCCTCCATCTTCCAGTCCCTGCTTCACTGCTTGCTGGGCAGAGCTCGCCCCACAAA GAAGAAAACAACCCAGGATTCCACAGATTTAGTGGATAACATGTCACCTGAAGAGATTGA GGCCTGGGAGCAGGAGCAGCTGAGCCAGCCTGTCTGTTTTGATTCCTGCTGTATTGACCA GTCTCCCTTCCAGCTGGTGGAGCAGACAACCCTGCACAAGACTCATACCCTGTTTTCACT CCTTGGCCTCCACCTCGCTTACGTGACCAGCATGGGGAAGCTCAGGGGCGTCCTGGCCCT GGAGGAGCTACAGAAGGCCATTGAGGGGCACACCAAGTCTGGGGTGCAGCTCCGCCCTCC CCTTGCCAGCTTCCGGAACACGACTTCAACTCGAAAGAGTACCGGGGCACCTCCATCTTC TGCAGAGAACTGGAACCTGCCTGAGGACAGGCCTGGGGCCACTGGAACAGGGGATGTGAT TGCTGCCTCCCCAGAGACCCCTGTGCCATCTCCTTCCCCAGAGCCCCCTCTCTCCCTGGC CCCAGGCAAGGTAGAGGGCGAGTTGGAGGAGCTGGAGCTGGTGGAGAGTCCAGGGCTGGA AGAGGAGCTGGCCGACATCTTGCAGGGCCCCAGCCTGCGATCCACAGACGAGGAGGATGA GGATGAACTGATCCTTTGACCCCCTCCCACGACCTCCT |
| Restriction Sites | Please inquire |
| ACCN | NM_000083 |
| Insert Size | 3000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The ORF of this clone has been fully sequenced and found to be a perfect match to NM_000083.1. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000083.1, NP_000074.1 |
| RefSeq Size | 3093 bp |
| RefSeq ORF | 3093 bp |
| Locus ID | 1180 |
| UniProt ID | P35523 |
| Protein Families | Druggable Genome, Ion Channels: Other, Transmembrane |
| Gene Summary | The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. The protein encoded by this gene regulates the electric excitability of the skeletal muscle membrane. Mutations in this gene cause two forms of inherited human muscle disorders: recessive generalized myotonia congenita (Becker) and dominant myotonia (Thomsen). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012] Transcript Variant: This variant (1) encodes the functional protein. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211343 | CLCN1 (Myc-DDK-tagged)-Human chloride channel 1, skeletal muscle (CLCN1) |
CNY 7,240.00 |
|
| RC211343L1 | Lenti ORF clone of Human chloride channel 1, skeletal muscle (CLCN1), Myc-DDK-tagged |
CNY 9,640.00 |
|
| RC211343L2 | Lenti ORF clone of Human chloride channel 1, skeletal muscle (CLCN1), mGFP tagged |
CNY 5,890.00 |
|
| RC211343L3 | Lenti ORF clone of Human chloride channel 1, skeletal muscle (CLCN1), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC211343L4 | Lenti ORF clone of Human chloride channel 1, skeletal muscle (CLCN1), mGFP tagged |
CNY 5,890.00 |
|
| RG211343 | CLCN1 (tGFP-tagged) - Human chloride channel 1, skeletal muscle (CLCN1) |
CNY 4,370.00 |
