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WHIP (WRNIP1) (NM_130395) Human Untagged Clone
CAT＃: SC120325
WRNIP1 (untagged)-Human Werner helicase interacting protein 1 (WRNIP1), transcript variant 2
CNY 4,776.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | bA420G6.2; CFAP93; FAP93; WHIP |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_130395, the custom clone sequence may differ by one or more nucleotides
ATGGAGGTGAGCGGGCCGGAAGACGACCCCTTCCTTTCGCAGCTGCACCAGGTGCAGTGCCCCGTGTGCC AGCAGATGATGCCCGCCGCGCACATCAACTCGCACCTGGACCGCTGTCTGCTGCTCCACCCGGCGGGGCA CGCGGAGCCCGCGGCCGGGTCGCACCGCGCCGGGGAGCGGGCCAAGGGGCCCTCGCCGCCCGGCGCCAAG AGGCGGCGGCTGTCGGAGAGCTCGGCGCTGAAGCAGCCAGCCACCCCGACGGCAGCCGAGAGCAGCGAGG GCGAGGGTGAGGAGGGCGACGACGGCGGCGAGACCGAGAGCCGCGAGAGCTACGACGCGCCGCCCACACC CAGCGGCGCCCGCCTTATCCCCGACTTCCCGGTGGCCCGCTCCAGCAGCCCCGGGAGGAAGGGGTCGGGG AAGAGGCCGGCGGCCGCCGCCGCGGCGGGGAGCGCGTCTCCGCGCAGCTGGGACGAGGCGGAGGCGCAGG AGGAGGAGGAGGCCGTGGGCGACGGCGATGGCGACGGGGACGCGGACGCGGACGGCGAGGACGACCCGGG GCACTGGGACGCGGACGCTGCCGAAGCCGCCACCGCCTTCGGGGCCAGTGGCGGGGGCCGCCCGCACCCC CGGGCGCTGGCTGCCGAGGAGATCCGACAGATGCTACAGGGCAAGCCGCTGGCCGACACGATGCGTCCTG ACACGCTGCAGGATTACTTCGGGCAGAGCAAGGCCGTGGGCCAGGATACCCTGCTGCGCTCGCTCCTGGA GACCAACGAAATCCCCTCGCTTATCCTGTGGGGGCCGCCGGGCTGCGGCAAGACCACTCTGGCTCACATC ATAGCCAGCAACAGCAAGAAACATAGCATAAGGTTTGTGACATTATCTGCAACAAATGCCAAGACAAATG ATGTGCGAGATGTCATAAAACAAGCTCAAAATGAAAAGAGCTTTTTCAAAAGGAAAACCATCCTTTTTAT TGATGAGATTCATCGGTTCAATAAATCTCAGCAGGTCAACGCTGCTCTTCTGAGCCGCTGTCGAGTGATT GTTCTTGAGAAGCTTCCAGTAGAGGCAATGGTGACTATTTTAATGCGAGCGATCAACTCCCTGGGAATCC ACGTCCTAGACTCTAGCCGTCCCACTGACCCTCTGAGCCACAGCAGCAACAGCAGCTCAGAGCCCGCCAT GTTCATAGAGGATAAAGCAGTAGACACCCTGGCTTACCTCAGTGACGGTGACGCCCGAGCTGGGTTGAAC GGACTGCAGCTGGCGGTGCTGGCTAGGTTAAGCTCTAGGAAGATGTTCTGTAAGAAGAGTGGGCAATCCT ATTCTCCCAGTAGAGTTCTGATCACAGAGAATGACGTGAAGGAGGGCCTACAGCGATCCCACATTTTATA TGACCGGGCAGGTGAGGAGCATTACAACTGCATCTCCGCCCTGCACAAGTCCATGCGGGGCTCAGACCAG AACGCCTCCCTCTACTGGCTGGCTCGCATGCTCGAGGGAGGAGAGGACCCACTCTACGTGGCACGGAGGC TTGTCAGGTTTGCCAGCGAGGACATAGGTCTGGCAGACCCGTCTGCGTTAACACAAGCGGTTGCTGCCTA CCAAGGCTGTCATTTTATAGGCATGCCTGAATGTGAGGTGCTTCTGGCCCAGTGTGTGGTCTACTTTGCC AGAGCCCCAAAGTCCATTGAGGTGTACAGCGCCTACAACAACGTCAAAGCCTGCCTGAGGAACCACCAGG GGCCACTGCCCCCCGTGCCCCTGCACCTGAGGAACGCGCCCACTAGGCTGATGAAGGATTTGGGCTATGG CAAAGGCTACAAGTACAACCCCATGTACAGCGAGCCTGTGGATCAGGAGTACCTGCCTGAAGAGTTGAGG GGGGTAGATTTCTTCAAGCAGAGGAGGTGCTGA >OriGene 5' read for NM_130395 unedited
GTTCACATTTGTATACGACTCCTATAGGGCGGCCGCGAATTCGCACGAGGGACGACCCGG GGCACTGGGACGCGGACGCTGCCGAAGCCGCCACCGCCTTCGGGGCCAGCGGCGGGGGCC GCCCGCACCCCCGGGCGCTGGCTGCCGAGGAGATCCGACAGATGCTACAGGGCAAGCCGC TGGCCGACACGATGCGTCCTGACACGCTGCAGGATTACTTCGGGCAGAGCAAGGCCGTGG GCCAGGATACCCTGCTGCGCTCGCTCCTGGAGACCAACGAAATCCCCTCGCTTATCCTGT GGGGGCCGCCGGGCTGCGGCAAGACCACTCTGGCTCACATCATAGCCAGCAACAGCAAGA AACATAGCATAAGGTTTGTGACATTATCTGCAACAAATGCCAAGACAAATGATGTGCGAG ATGTCATAAAACAAGCTCAAAATGAAAAGAGCTTTTTCAAAAGGAAAACCATCCTTTTTA TTGATGAGATTCATCGGTTCAATAAATCTCAGCAGGACACTTTCCTTCCTCACGTGGAAT GTGGGACGATCACTCTGATTGGGGCAACCACTGAAAACCCTTCCTTCCAGGTCAACGCTG CTCTTCTGAGCCGCTGTCGAGTGATTGTTCTTGAGAAGCTTCCAGTAGAGGCAATGGTGA CTATNNTAATGCGAGCGATCAACTCCCTGGGAATCCACGTCCTAGACTCTAGCCGTCCCA CTGACCCTCTGAGCCACAGCAGCAACAGCAGCTCAGAGCCCGCCATGGTCATAGAGGATA AAGCAGTAGACACCCTGGCTTACCTCAGTGACGGTGACGCCCGAGCTGGGTTGAACGGAC TGCAGCTGGGCGTGCTGGCTANGTTAAGCTCTNAGAAAGATGTTCTGTAGAAGAGTGGGG CATCCTATT >OriGene 3' read for NM_130395 unedited
TTTGGCCGCGGCCGCAATCTAGNGTCGAGTTTTTTTTTTTTTTTTTTACTTTGAAATAGT TTTATTGGCTCGTAAGACCTTTGCATATAAAAAAATACCCAAAACACTATGCAGTATTAA ATCACAATTACATTTTTTTACCAATTAAAACTACCCAGAATATACATTTTTTAAAGAAAA GAAAATCCTACAGAACTGAATTCTGAAATGACATTATGACTTAAATACTATGACAAAATA GATAATTCCTTATAACATTAATTCATTGCACAAAGCTGCCAGGTATTTTCATAAGCATAA CCGCTGCACCGAGTGCAAATGAACACAATTTCAAAGTTACACATTTATTCGAAAGAACTG CGCCTCCACCTATGGAACTCTTAAATTTCTGGCACAAAATGTTGGTCTGTTCTAACTTCC ACCAGGCAACCAACTTTGCAATCCACTAACTTTCTTTCTGGCCCTCCCTTAAAAAAGCAA CATCCTTCTGCTGTCGTGCCCTGAGGAGTCAGCACCTCCTCTGCTTGAAGAAATCTACCC CCCTCAACTCTTCAGGCAGGTACTCCTGATCCACAGGCTCGCTGTACATGGGGTTGTACT TGTAGCCTTTGCCATAGCCCAAATCCTTCATCAGCCTAGTGGGCGCGTTCCTCAGGTGCA GGGGCACGGGGGGCAGTGGCCCCTGGTGGTTNCTCAGGCAGGCTTTGACGTTGTTGTAGG CGCTGGACACTCAATGGGACTTGGGGCTCTGGCAAGTANACCACCACTGGGCCGNAAGCA CTNACATTCAGCATGCTATAAATGACGCCTGGNTAGCAGCACCGCTTGTGTAACGCANAA GGTCTGGCAGACTTATGTCTGCTTGCAAACTGACAGNCTNCGGGCAAGTAAAGTGTTTCT TTCT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_130395 |
| Insert Size | 2250 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_130395.1, NP_569079.1 |
| RefSeq Size | 2592 bp |
| RefSeq ORF | 1923 bp |
| Locus ID | 56897 |
| UniProt ID | Q96S55 |
| Domains | AAA, AAA, ZnF_Rad18 |
| Gene Summary | Werner's syndrome is a rare autosomal recessive disorder characterized by accelerated aging that is caused by defects in the Werner syndrome ATP-dependent helicase gene (WRN). The protein encoded by this gene interacts with the exonuclease-containing N-terminal portion of the Werner protein. This protein has a ubiquitin-binding zinc-finger domain in the N-terminus, an ATPase domain, and two leucine zipper motifs in the C-terminus. It has sequence similarity to replication factor C family proteins and is conserved from E. coli to human. This protein likely accumulates at sites of DNA damage by interacting with polyubiquinated proteins and also binds to DNA polymerase delta and increases the initiation frequency of DNA polymerase delta-mediated DNA synthesis. This protein also interacts with nucleoporins at nuclear pore complexes. Two transcript variants encoding different isoforms have been isolated for this gene. [provided by RefSeq, Jul 2012] Transcript Variant: This variant (2) utilizes a different acceptor splice site for an internal coding exon, compared to transcript variant 1. This variant maintains the same reading frame but encodes an isoform (2) which is 25 aa shorter than isoform 1. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202950 | WRNIP1 (Myc-DDK-tagged)-Human Werner helicase interacting protein 1 (WRNIP1), transcript variant 2 |
CNY 4,768.00 |
|
| RC202950L1 | Lenti ORF clone of Human Werner helicase interacting protein 1 (WRNIP1), transcript variant 2, Myc-DDK-tagged |
CNY 7,168.00 |
|
| RC202950L2 | Lenti ORF clone of Human Werner helicase interacting protein 1 (WRNIP1), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC202950L3 | Lenti ORF clone of Human Werner helicase interacting protein 1 (WRNIP1), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC202950L4 | Lenti ORF clone of Human Werner helicase interacting protein 1 (WRNIP1), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG202950 | WRNIP1 (tGFP-tagged) - Human Werner helicase interacting protein 1 (WRNIP1), transcript variant 2 |
CNY 4,370.00 |
|
| SC320312 | WRNIP1 (untagged)-Human Werner helicase interacting protein 1 (WRNIP1), transcript variant 2 |
CNY 4,776.00 |
