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WHIP (WRNIP1) (NM_130395) Human Untagged Clone
CAT＃: SC320312
WRNIP1 (untagged)-Human Werner helicase interacting protein 1 (WRNIP1), transcript variant 2
CNY 4,776.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | bA420G6.2; CFAP93; FAP93; WHIP |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_130395.1
CATGAGCGGCGCCCTCCTCCGGCCCGCGAGCGTCCTGCTGGTTCCCCGAGCGAGGGTCTC
GCGGCGCGGGGCCTAGCGGAGGGCATCGAAGGCCTCCGCGTGCGCACGGGTTGCTGCGGC CGCGCCGGGCGCCGGGGAGGGCGGCGGCCGCCATGGAGGTGAGCGGGCCGGAAGACGACC CCTTCCTTTCGCAGCTGCACCAGGTGCAGTGCCCCGTGTGCCAGCAGATGATGCCCGCCG CGCACATCAACTCGCACCTGGACCGCTGTCTGCTGCTCCACCCGGCGGGGCACGCGGAGC CCGCGGCCGGGTCGCACCGCGCCGGGGAGCGGGCCAAGGGGCCCTCGCCGCCCGGCGCCA AGAGGCGGCGGCTGTCGGAGAGCTCGGCGCTGAAGCAGCCAGCCACCCCGACGGCAGCCG AGAGCAGTGAGGGCGAGGGCGAGGAGGGCGACGACGGCGGCGAGACCGAGAGCCGCGAGA GCTACGACGCGCCGCCCACACCCAGCGGCGCCCGCCTTATCCCCGACTTCCCGGTGGCCC GCTCCAGCAGCCCCGGGAGGAAGGGGTCGGGGAAGAGGCCGGCGGCCGCCGCCGCGGCGG GGAGCGCGTCTCCGCGCAGCTGGGACGAGGCGGAGGCGCAGGAGGAGGAGGAGGCCGTGG GCGACGGCGATGGCGACGGGGACGCGGACGCGGACGGCGAGGACGACCCGGGGCACTGGG ACGCGGACGCTGCCGAAGCCGCCACCGCCTTCGGGGCCAGCGGCGGGGGCCGCCCGCACC CCCGGGCGCTGGCTGCCGAGGAGATCCGACAGATGCTACAGGGCAAGCCGCTGGCCGACA CGATGCGTCCTGACACGCTGCAGGATTACTTCGGGCAGAGCAAGGCCGTGGGCCAGGATA CCCTGCTGCGCTCGCTCCTGGAGACCAACGAAATCCCCTCGCTTATCCTGTGGGGGCCGC CGGGCTGCGGCAAGACCACTCTGGCTCACATCATAGCCAGCAACAGCAAGAAACATAGCA TAAGGTTTGTGACATTATCTGCAACAAATGCCAAGACAAATGATGTGCGAGATGTCATAA AACAAGCTCAAAATGAAAAGAGCTTTTTCAAAAGGAAAACCATCCTTTTTATTGATGAGA TTCATCGGTTCAATAAATCTCAGCAGGTCAACGCTGCTCTTCTGAGCCGCTGTCGAGTGA TTGTTCTTGAGAAGCTTCCAGTAGAGGCAATGGTGACTATTTTAATGCGAGCGATCAACT CCCTGGGAATCCACGTCCTAGACTCTAGCCGTCCCACTGACCCTCTGAGCCACAGCAGCA ACAGCAGCTCAGAGCCCGCCATGTTCATAGAGGATAAAGCAGTAGACACCCTGGCTTACC TCAGTGACGGTGACGCCCGAGCTGGGTTGAACGGACTGCAGCTGGCGGTGCTGGCTAGGT TAAGCTCTAGGAAGATGTTCTGTAAGAAGAGTGGGCAATCCTATTCTCCCAGTAGAGTTC TGATCACAGAGAATGACGTGAAGGAGGGCCTACAGCGATCCCACATTTTATATGACCGGG CAGGTGAGGAGCATTACAACTGCATCTCCGCCCTGCACAAGTCCATGCGGGGCTCAGACC AGAACGCCTCCCTCTACTGGCTGGCTCGCATGCTCGAGGGAGGAGAGGACCCACTCTACG TGGCACGGAGGCTTGTCAGGTTTGCCAGCGAGGACATAGGTCTGGCAGACCCGTCTGCGT TAACACAAGCGGTTGCTGCCTACCAAGGCTGTCATTTTATAGGCATGCCTGAATGTGAGG TGCTTCTGGCCCAGTGTGTGGTCTACTTTGCCAGAGCCCCAAAGTCCATTGAGGTGTACA GCGCCTACAACAACGTCAAAGCCTGCCTGAGGAACCACCAGGGGCCACTGCCCCCCGTGC CCCTGCACCTGAGGAACGCGCCCACTAGGCTGATGAAGGATTTGGGCTATGGCAAAGGCT ACAAGTACAACCCCATGTACAGCGAGCCTGTGGATCAGGAGTACCTGCCTGAAGAGTTGA GGGGGGTAGATTTCTTCAAGCAGAGGAGGTGCTGACTCCTCAGGGCACGACAGCAGAAGG ATGTTGCTTTTTTAAGGGAGGGCCAGAAAGAAAGTTAGTGGATTGCAAAGTTGGTTGCCT GGTGGAAGTTAGAACAGACCAACATTTTGTGCCAGAAATTTAAGAGTTCCATAGGTGGAG GCGCAGTTCTTTCGAATAAATGTGTAACTTTGAAATTGTGTTCATTTGCACTCGGTGCAG CGGTTATGCTTATGAAAATACCTGGCAGCTTTGTGCAATGAATTAATGTTATAAGGAATT ATCTATTTTGTCATAGTATTTAAGTCATAATGTCATTTCAGAATTCAGTTCTGTAGGATT TTCTTTTCTTTAAAAAATGTATATTCTGGGTAGTTTTAATTGGTAAAAAAATGTAATTGT GATTTAATACTGCATAGTGTTTTGGGTATTTTTTTTATATGCAAAGGTCTTACGAGCCAA TAAAACTATTTCAAAGTAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_130395 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_130395.1, NP_569079.1 |
| RefSeq Size | 2592 bp |
| RefSeq ORF | 1923 bp |
| Locus ID | 56897 |
| UniProt ID | Q96S55 |
| Domains | AAA, AAA, ZnF_Rad18 |
| Gene Summary | Werner's syndrome is a rare autosomal recessive disorder characterized by accelerated aging that is caused by defects in the Werner syndrome ATP-dependent helicase gene (WRN). The protein encoded by this gene interacts with the exonuclease-containing N-terminal portion of the Werner protein. This protein has a ubiquitin-binding zinc-finger domain in the N-terminus, an ATPase domain, and two leucine zipper motifs in the C-terminus. It has sequence similarity to replication factor C family proteins and is conserved from E. coli to human. This protein likely accumulates at sites of DNA damage by interacting with polyubiquinated proteins and also binds to DNA polymerase delta and increases the initiation frequency of DNA polymerase delta-mediated DNA synthesis. This protein also interacts with nucleoporins at nuclear pore complexes. Two transcript variants encoding different isoforms have been isolated for this gene. [provided by RefSeq, Jul 2012] Transcript Variant: This variant (2) utilizes a different acceptor splice site for an internal coding exon, compared to transcript variant 1. This variant maintains the same reading frame but encodes an isoform (2) which is 25 aa shorter than isoform 1. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202950 | WRNIP1 (Myc-DDK-tagged)-Human Werner helicase interacting protein 1 (WRNIP1), transcript variant 2 |
CNY 4,768.00 |
|
| RC202950L1 | Lenti ORF clone of Human Werner helicase interacting protein 1 (WRNIP1), transcript variant 2, Myc-DDK-tagged |
CNY 7,168.00 |
|
| RC202950L2 | Lenti ORF clone of Human Werner helicase interacting protein 1 (WRNIP1), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC202950L3 | Lenti ORF clone of Human Werner helicase interacting protein 1 (WRNIP1), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC202950L4 | Lenti ORF clone of Human Werner helicase interacting protein 1 (WRNIP1), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG202950 | WRNIP1 (tGFP-tagged) - Human Werner helicase interacting protein 1 (WRNIP1), transcript variant 2 |
CNY 4,370.00 |
|
| SC120325 | WRNIP1 (untagged)-Human Werner helicase interacting protein 1 (WRNIP1), transcript variant 2 |
CNY 4,776.00 |
