NBR1 (NM_001291571) Human Tagged ORF Clone
CAT#: RG239803
- TrueORF®
NBR1 (tGFP-tagged) - Human neighbor of BRCA1 gene 1 (NBR1), transcript variant 4
ORF Plasmid: DDK
"NM_001291571" in other vectors (2)
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CNY 9,690.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | TurboGFP |
Synonyms | 1A1-3B; IAI3B; M17S2; MIG19 |
Vector | pCMV6-AC-GFP |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RG239803 representing NM_001291571.
Blue=ORF Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGAACCACAGGTTACTCTAAATGTGACTTTTAAAAATGAAATTCAAAGCTTTCTGGTTTCTGATCCA GAAAATACAACTTGGGCTGATATCGAAGCTATGGTAAAAGTTTCATTTGATCTGAATACTATTCAAATA AAATACCTGGATGAGGAAAATGAAGAGGTATCCATCAACAGTCAAGGAGAATATGAAGAAGCGCTTAAG ATGGCAGTTAAACAGGGAAACCAACTGCAGATGCAAGTCCACGAAGGGCACCATGTCGTTGATGAAGCC CCACCCCCAGTTGTAGGAGCAAAACGACTAGCTGCCAGGGCAGGGAAGAAGCCACTTGCACATTACTCT TCACTGGTGAGAGTCTTGGGATCAGACATGAAGACCCCAGAGGATCCTGCAGTGCAGTCGTTTCCACTT GTTCCATGTGACACAGACCAGCCTCAAGACAAGCCCCCAGACTGGTTCACAAGCTACCTGGAGACGTTC AGAGAACAAGTGGTTAACGAAACGGTTGAGAAGCTTGAACAGAAATTACATGAAAAGCTTGTCCTCCAG AACCCATCCTTGGGTTCTTGTCCCTCAGAAGTCTCAATGCCTACTTCAGAAGAAACATTGTTTTTGCCA GAAAACCAGTTCAGCTGGCATATTGCTTGCAACAACTGCCAAAGAAGGATTGTTGGTGTCCGCTACCAG TGTAGCCTATGCCCATCCTACAATATCTGTGAAGATTGTGAAGCAGGGCCATATGGCCATGACACTAAC CACGTCCTGCTGAAGTTGCGGAGACCTGTTGTGGGCTCCTCTGAACCGTTCTGTCACTCAAAGTACTCT ACTCCTCGTCTTCCTGCTGCTCTGGAACAAGTCAGGCTCCAGAAACAGGTTGATAAGAACTTTCTTAAA GCAGAAAAGCAAAGGTTGCGAGCTGAGAAGAAACAACGTAAAGCAGAGGTCAAGGAACTTAAAAAGCAG CTTAAACTCCATAGGAAAATTCACCTGTGGAATTCAATCCATGGACTCCAGAGCCCCAAGTCTCCTTTA GGCCGACCTGAGAGCTTGCTCCAGTCTAATACCCTGATGCTCCCTTTGCAGCCCTGTACCTCCGTTATG CCAATGCTCAGTGCAGCATTTGTGGATGAGAATTTGCCTGATGGGACTCACCTTCAGCCAGGAACCAAG TTTATCAAACACTGGAGGATGAAAAATACAGGAAATGTAAAGTGGAGTGCAGACACAAAGCTCAAGTTC ATGTGGGGAAACCTGACTTTGGCTTCCACAGAAAAGAAGGATGTTTTGGTTCCCTGCCTCAAGGCCGGC CATGTGGGAGTTGTATCTGTGGAGTTCATTGCCCCAGCCTTGGAGGGAACGTATACTTCCCATTGGCGT CTTTCTCACAAAGGCCAGCAATTTGGGCCTCGGGTCTGGTGCAGTATCATAGTAGATCCTTTCCCCTCC GAAGAGAGCCCTGATAACATTGAAAAGGGCATGATCAGCTCAAGCAAAACTGATGATCTCACCTGCCAG CAAGAGGAAACTTTTCTTCTGGCTAAAGAAGAAAGACAGCTTGGTGAAGTGACTGAGCAGACAGAAGGG ACAGCAGCCTGCATCCCACAGAAGGCAAAAAATGTTGCCAGTGAGAGGGAGCTCTACATCCCATCTGTG GATCTTCTGACTGCCCAGGACCTGCTGTCCTTTGAGCTGTTGGATATAAACATTGTTCAAGAGTTGGAG AGAGTGCCCCACAACACCCCTGTGGATGTGACTCCCTGCATGTCTCCTCTGCCACATGACAGTCCTTTA ATAGAGAAGCCAGGCTTGGGGCAGATAGAGGAAGAGAATGAAGGGGCAGGATTTAAAGCACTTCCTGAT TCTATGGTGTCAGTAAAGAGGAAGGCTGAGAACATTGCTTCTGTGGAGGAAGCAGAAGAAGACCTGAGT GGGACCCAGTTTGTGTGTGAGACAGTAATCCGATCCCTTACCTTGGATGCTGCCCCAGACCACAACCCT CCTTGCAGACAGAAGTCCTTGCAGATGACATTTGCCTTGCCTGAAGGACCACTTGGAAATGAGAAGGAG GAGATTATCCATATCGCTGAGGAAGAAGCTGTCATGGAGGAGGAGGAGGATGAGGAGGATGAGGAGGAG GAGGATGAGCTCAAAGATGAAGTTCAAAGTCAGTCCTCTGCTTCCTCAGAGGATTACATCATCATCCTG CCTGAGTGCTTTGATACCAGCCGCCCCCTGGGGGATTCTATGTACAGCTCTGCGCTCTCACAGCCAGGC CTGGAGCGAGGTGCTGAAGGCAAGCCTGGGGTTGAGGCTGGGCAGGAACCAGCTGAGGCTGGGGAAAGA CTCCCTGGAGGGGAGAACCAGCCACAGGAGCACAGCATAAGTGACATCCTCACGACCTCACAGACTCTG GAAACAGTGCCCCTAATCCCAGAGGTAGTGGAGCTTCCACCGTCACTGCCCAGGAGCTCTCCTTGTGTA CATCATCATGGTTCCCCAGGAGTGGATTTACCAGTTACCATACCAGAAGTTTCTTCAGTCCCTGATCAG ATCAGAGGAGAGCCCAGAGGCTCATCAGGACTTGTAAACAGCAGACAGAAGAGCTATGACCACTCAAGG CACCATCATGGGAGCAGCATTGCTGGAGGACTGGTGAAGGGGGCTTTGTCTGTTGCTGCCTCTGCATAC AAGGCCCTGTTTGCTGGGCCACCAGTCACTGCACAGGGTCTCTGGGGCTTGCTGTCATTCCTTCATCTG GCCAAAAAATGCTTCTTCCTGAAAGCCCCGAGTGAAGCATTCTCCTGGTTC ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAAAC >Peptide sequence encoded by RG239803
Blue=ORF Red=Cloning site Green=Tag(s) MEPQVTLNVTFKNEIQSFLVSDPENTTWADIEAMVKVSFDLNTIQIKYLDEENEEVSINSQGEYEEALK MAVKQGNQLQMQVHEGHHVVDEAPPPVVGAKRLAARAGKKPLAHYSSLVRVLGSDMKTPEDPAVQSFPL VPCDTDQPQDKPPDWFTSYLETFREQVVNETVEKLEQKLHEKLVLQNPSLGSCPSEVSMPTSEETLFLP ENQFSWHIACNNCQRRIVGVRYQCSLCPSYNICEDCEAGPYGHDTNHVLLKLRRPVVGSSEPFCHSKYS TPRLPAALEQVRLQKQVDKNFLKAEKQRLRAEKKQRKAEVKELKKQLKLHRKIHLWNSIHGLQSPKSPL GRPESLLQSNTLMLPLQPCTSVMPMLSAAFVDENLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKF MWGNLTLASTEKKDVLVPCLKAGHVGVVSVEFIAPALEGTYTSHWRLSHKGQQFGPRVWCSIIVDPFPS EESPDNIEKGMISSSKTDDLTCQQEETFLLAKEERQLGEVTEQTEGTAACIPQKAKNVASERELYIPSV DLLTAQDLLSFELLDINIVQELERVPHNTPVDVTPCMSPLPHDSPLIEKPGLGQIEEENEGAGFKALPD SMVSVKRKAENIASVEEAEEDLSGTQFVCETVIRSLTLDAAPDHNPPCRQKSLQMTFALPEGPLGNEKE EIIHIAEEEAVMEEEEDEEDEEEEDELKDEVQSQSSASSEDYIIILPECFDTSRPLGDSMYSSALSQPG LERGAEGKPGVEAGQEPAEAGERLPGGENQPQEHSISDILTTSQTLETVPLIPEVVELPPSLPRSSPCV HHHGSPGVDLPVTIPEVSSVPDQIRGEPRGSSGLVNSRQKSYDHSRHHHGSSIAGGLVKGALSVAASAY KALFAGPPVTAQGLWGLLSFLHLAKKCFFLKAPSEAFSWF TRTRPLEMESDESGLPAMEIECRITGTLNGVEFELVGGGEGTPEQGRMTNKMKSTKGALTFSPYLLSHV MGYGFYHFGTYPSGYENPFLHAINNGGYTNTRIEKYEDGGVLHVSFSYRYEAGRVIGDFKVMGTGFPED SVIFTDKIIRSNATVEHLHPMGDNDLDGSFTRTFSLRDGGYYSSVVDSHMHFKSAIHPSILQNGGPMFA FRRVEEDHSNTELGIVEYQHAFKTPDADAGEERV |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_001291571 |
ORF Size | 2811 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reference Data | |
RefSeq | NM_001291571.2 |
RefSeq Size | 3387 bp |
RefSeq ORF | 2814 bp |
Locus ID | 4077 |
UniProt ID | Q14596 |
Protein Families | Druggable Genome |
MW | 104.3 kDa |
Gene Summary | The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014] |
Documents
Product Manuals |
FAQs |
SDS |