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Numbl (NM_010950) Mouse Untagged Clone
CAT＃: MC202603
Numbl (untagged) - Mouse numb-like (Numbl), (10ug)
CNY 2,000.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | nbl |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC068116 sequence for NM_010950
CTGGATGTCCCGCAGCGCGGCGGCCAGCGGCGGACCCAGGAGACCTGATCAGCATTTGTCCCCAGCCCCC TGTGGGGCCTCGGGGCCCCCTGAAACCTTCAGGACGGAGTCAGACGGGGCAGGCACCATGAACAAGTTAC GGCAGAGTCTGCGGCGGAGGAAGCCAGCCTATGTGCCTGAGGCATCACGCCCACACCAGTGGCAGGCAGA TGAGGATGCGGTGCGCAAAGGCACCTGCAGCTTCCCTGTTAGGTACCTGGGCCACGTGGAAGTGGAGGAG TCCCGGGGAATGCACGTTTGTGAAGATGCTGTGAAGAAGCTGAAGGCGATGGGCCGGAAGTCCGTGAAGT CTGTCCTGTGGGTGTCAGCTGATGGGCTCCGAGTGGTGGATGACAAGACCAAGGACCTGCTGGTAGACCA GACCATTGAGAAGGTCTCCTTCTGTGCTCCTGATCGCAACCTGGACAAGGCTTTCTCCTACATATGCCGC GACGGCACCACACGCCGCTGGATCTGCCACTGCTTCCTGGCCCTCAAGGACTCTGGTGAGAGGCTGAGCC ATGCTGTGGGCTGCGCGTTCGCCGCCTGCCTGGAGAGGAAGCAGCGACGGGAGAAGGAATGCGGAGTCAC CGCCGCCTTCGACGCCAGTCGCACCAGCTTTGCCCGTGAGGGCTCCTTCCGCCTGTCGGGGGGCGGGCGG CCTGCGGAGCGCGAGGCAGGGGACAAGAAGAAAGCCGAAGCAGCAGCTGCTCCTGCTGTGGCTCCTGGAC CTGCCCAGCCTGGGCACGTTTCTCCGACACCAGCCACCACATCCCCTGGAGAGAAGGGAGAGGCGGGCAC CCCAGTGGCTGCAGGCACCACTGCTGCTGCCATTCCCCGGCGCCACGCACCTCTGGAGCAGCTGGTTCGC CAGGGCTCCTTTCGTGGGTTCCCTGCCCTCAGTCAGAAGAACTCACCTTTCAAACGTCAGCTGAGCCTAC GGTTGAATGAGCTGCCATCAACACTGCAGCGCCGCACGGACTTCCAGGTGAAGGGCACAGTGCCTGAGAT GGAGCCTCCTGGTACCGGGGACAGCGATGGCATCAATGCTCTGTGCACACAGATCAGCTCGTCTTTCGCC AGCGCTGGGGCCCCAGCGTCAGGGCCACCACCTGCCACAACAGGGACTTCTGCCTGGGGTGAGCCCTCCG TACCCGCTGCAGCTGCCTTCCAGCCTGGGCACAAGCGGACACCCTCTGAGGCTGAGCGATGGTTGGAGGA AGTGTCCCAGGTGGCTAAGGCCCAGCAGCAACAGCAACAGCAGCAGCAGCAACAACAGCAGCAGCAAGCC ACCTCCGTGCCACCAATGCCCACCATGGCCCCCACCCTTCAACCCTTTTCTGCCCCAGTGGGGCCCTTTG ACACTGCAGCTGCCCAAGTGGCTGTTTTCCTGCCGCCCACACATATGCAGCCTCCGTTTGTGCCCGCCTA CCCAGGTCTGGGTTATCCACCAATGCCCCGGGTGCCTGTGGTGGGCATCACACCTTCACAGATGGTAGCC AACGCCTTCTGCTCAGCTGCCCAGCTCCAGCCCCAACCTGCCACACTGCTTGGAAAAGCTGGGGCCTTCC CCCCACCTGCTGCACCCAGTGCCCCTGGGGGCCAGGCCCGTCCGCGCCCCAATGGGGCTCCCTGGCCCCC AGAGCCAGCGCCTGCCCCTGCCCCTGAGTTGGACCCCTTCGAGGCCCAGTGGGCGGCACTAGAAGGCAAA CCCGCTGTGGAGAAACCCTTCAACCCCTTCTCTGGTGACTTGCAGAAGACCTTCGAGATTGAACTGTAGC CCAAATTGCCCTGCTCCCGCTCCATCAGCCCCAGGTGTACCGCGCTCAGGAGGGGAGGCCCAGCCTCTAT CCTAGTGTTGCTCCCTGAGCTGCGCCCCTCAATGCTCCCTCTAAGCCCTTCTCTCCACCACCCCTCACAA ACCACTACAGAACCAATATTGTGATGCCTAGGTTTTGCCAAGATGGAATTCAGGGATGGACCCAGCCTGG CTAAGGGAACCATTTCACTGCCGGACTTAGGCTGGTGATGCCCCTTCCCCAGCCCCAGTCATGGAATGCC CTCTGTTCAAGCTACTTTCCCTAGTTTCTGTTGTGCCCTTCCACCTTCCAGTGTTGGGCAGGGTGGAGGA GGGAGGCCCACTTAAGCCTGGTCCGTCCTCTCCTTGTCCCATACACACAGCACAAGCTAAGGGCTTCCTC TCTGCCCACGCTGTGTTCACTGCCAATGCTGTGCTTGCCCTGGCCCCCTCCCCGATTCGATTCGGGGCGT GTCTTCCGGAGGGCCAAGGTCTCACGGGGTGGGGCCCGACTGGGGGCCCAGGAGAGGGGCGGTGGGAGGG ATGAAGACTCTGTTACCTCATGTCGGTGCCCGCTGGGGAGGGGTCCCAGGAGAAGAAGAAGGGGGTGCCT GGCGGGTACTTTTCTATCTTTTATTTCCAGATTTTTTTTGTATCTAAACTTGCAGATTTGTATTATACAA GGACAGCCAATAAAGGAAGAATATAATGGTGAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | AscI-NotI |
| ACCN | NM_010950 |
| Insert Size | 1815 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | BC068116, AAH68116 |
| RefSeq Size | 2571 bp |
| RefSeq ORF | 1815 bp |
| Locus ID | 18223 |
| UniProt ID | O08919 |
| Gene Summary | Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of embryonic neurogenesis. Also required postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. Negative regulator of NF-kappa-B signaling pathway. The inhibition of NF-kappa-B activation is mediated at least in part, by preventing MAP3K7IP2 to interact with polyubiquitin chains of TRAF6 and RIPK1 and by stimulating the 'Lys-48'-linked polyubiquitination and degradation of TRAF6 in cortical neurons.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG209340 | Numbl (tGFP-tagged) - Mouse numb-like (Numbl) |
CNY 5,040.00 |
|
| MR209340 | Numbl (Myc-DDK-tagged) - Mouse numb-like (Numbl) |
CNY 4,504.00 |
|
| MR209340L3 | Lenti ORF clone of Numbl (Myc-DDK-tagged) - Mouse numb-like (Numbl) |
CNY 6,460.00 |
|
| MR209340L4 | Lenti ORF clone of Numbl (mGFP-tagged) - Mouse numb-like (Numbl) |
CNY 6,460.00 |
