United States
Germany
Japan
United Kingdom
China
Numbl (NM_010950) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR209340L3V
- LentiORF®
-
Lenti ORF particles, Numbl (Myc-DDK-tagged) - Mouse numb-like (Numbl), 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 10,735.00
货期*
详询
规格
Product images
经常一起买 (2)
Specifications
| Product Data | |
| Product Name | Numbl (NM_010950) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | nbl |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_010950 |
| ORF Size | 1815 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR209340).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_010950.2, NP_035080.2 |
| RefSeq Size | 2733 bp |
| RefSeq ORF | 1815 bp |
| Locus ID | 18223 |
| Gene Summary | Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of embryonic neurogenesis. Also required postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. Negative regulator of NF-kappa-B signaling pathway. The inhibition of NF-kappa-B activation is mediated at least in part, by preventing MAP3K7IP2 to interact with polyubiquitin chains of TRAF6 and RIPK1 and by stimulating the 'Lys-48'-linked polyubiquitination and degradation of TRAF6 in cortical neurons.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
You may also need
Customer
Reviews
Loading...
