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RRM1 Rabbit Polyclonal Antibody
CAT＃: TA323396S
Anti-RRM1 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
Specifications
| Product Data | |
| Applications | WB |
| Recommend Dilution | WB: 500-2000 WB positive control: Hela cells |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Fusion protein corresponding to C terminal 226 amino acids of human ribonucleotide reductase M1 |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 90 kDa |
| Gene Name | ribonucleotide reductase catalytic subunit M1 |
| Database Link | |
| Background | This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase; an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5; an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome; Wilms tumor; rhabdomyosarcoma; adrenocrotical carcinoma; and lung; ovarian; and breast cancer. This gene may play a role in malignancies and disease that involve this region. |
| Synonyms | R1; RIR1; RR1 |
| Reference Data | |
| Protein Families | Druggable Genome |
| Protein Pathways | Glutathione metabolism, Metabolic pathways, Purine metabolism, Pyrimidine metabolism |
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RRM1 Rabbit Polyclonal Antibody
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