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LOX Rabbit Polyclonal Antibody
CAT＃: TA321469S
Anti-LOX Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommend Dilution | WB: 200-1000 WB positive control: Rat brain tissue lysate IHC: 20-100 Positive control: Human liver cancer Predicted cell location: Secreted |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 248-262 amino acids of human lysyl oxidase |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 47 kDa |
| Gene Name | lysyl oxidase |
| Database Link | |
| Background | The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins; the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene. |
| Synonyms | MGC105112 |
| Reference Data | |
| Protein Families | Druggable Genome, Secreted Protein |
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