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PDX1 Rabbit Polyclonal Antibody
CAT＃: TA321081S
Anti-PDX1 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommend Dilution | WB: 500-2000 WB positive control: Hela and Jurkat cells IHC: 15-50 Positive control: Human colon cancer Predicted cell location: Cytoplasm |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide peptide corresponding to a region derived from 18-31 amino acids of human pancreatic and duodenal homeobox 1 |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 31 kDa |
| Gene Name | pancreatic and duodenal homeobox 1 |
| Database Link | |
| Background | The protein encoded by this gene is a transcriptional activator of several genes; including insulin; somatostatin; glucokinase; islet amyloid polypeptide; and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis; which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM); as well as maturity onset diabetes of the young type 4 (MODY4). |
| Synonyms | GSF; IDX-1; IPF1; IUF1; MODY4; PAGEN1; PDX-1; STF-1 |
| Reference Data | |
| Protein Families | Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors |
| Protein Pathways | Maturity onset diabetes of the young, Type II diabetes mellitus |
Documents
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Rabbit anti-PDX1 Polyclonal Antibody
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