Ppt1 Mouse siRNA Oligo Duplex (Locus ID 19063)
CAT#: SR409088
Ppt1 (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each
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CNY 4,090.00
货期*
4周
规格
Cited in 1 publication. |
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经常一起买 (2)
Specifications
Product Data | |
Purity | HPLC purified |
Quality Control | Tested by ESI-MS |
Sequences | Available with shipment |
Stability | One year from date of shipment when stored at -20°C. |
# of transfections | Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM). |
Note | Single siRNA duplex (10nmol) can be ordered. |
Reference Data | |
RefSeq | NM_008917 |
Synonyms | 9530043G02Rik; AA960502; C77813; CLN1; D4Ertd184e; INCL; PPT |
Components | Ppt1 (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 19063)Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmolIncluded - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml |
Summary | Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons.[UniProtKB/Swiss-Prot Function] |
Performance Guranteed | OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency. For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required). |
Citations (1)
The use of this RNAi has been cited in the following citations: |
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PPT1 inhibition enhances the antitumor activity of anti-PD-1 antibody in melanoma
,Sharma, G;Ojha, R;Noguera-Ortega, E;Rebecca, VW;Attanasio, J;Liu, S;Piao, S;Lee, JJ;Nicastri, MC;Harper, SL;Ronghe, A;Jain, V;Winkler, JD;Speicher, DW;Mastio, J;Gimotty, PA;Xu, X;Wherry, EJ;Gabrilovich, DI;Amaravadi, RK;,
JCI Insight
,PubMed ID 32780726
[PPT1]
|
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