Argonaute 2 (AGO2) Human siRNA Oligo Duplex (Locus ID 27161)
CAT#: SR323843
AGO2 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each
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SR323843 is the updated version of SR309012.
CNY 4,090.00
货期*
5周
规格
Cited in 3 publications. |
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经常一起买 (3)
Specifications
Product Data | |
Purity | HPLC purified |
Quality Control | Tested by ESI-MS |
Sequences | Available with shipment |
Stability | One year from date of shipment when stored at -20°C. |
# of transfections | Approximately 330 transfections/2nmol in 24-well plate under optimized conditions (final conc. 10 nM). |
Note | Single siRNA duplex (10nmol) can be ordered. |
Reference Data | |
RefSeq | NM_001164623, NM_012154 |
Synonyms | CASC7; EIF2C2; LESKRES; LINC00980; PPD; Q10 |
Components | AGO2 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each (Locus ID 27161)Included - SR30004, Trilencer-27 Universal Scrambled Negative Control siRNA Duplex - 2 nmolIncluded - SR30005, RNAse free siRNA Duplex Resuspension Buffer - 2 ml |
Summary | This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] |
Performance Guranteed | OriGene guarantees that at least two of the three Dicer-Substrate duplexes in the kit will provide at least 70% or more knockdown of the target mRNA when used at 10 nM concentration by quantitative RT-PCR when the TYE-563 fluorescent transfection control duplex (cat# SR30002) indicates that >90% of the cells have been transfected and the HPRT positive control (cat# SR30003) provides 90% knockdown efficiency. For non-conforming siRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the siRNA kit. To arrange for a free replacement with newly designed duplexes, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled siRNA control (quantitative RT-PCR data required). |
Citations (3)
The use of this RNAi has been cited in the following citations: |
---|
miRNA-dependent regulation of STIM1 expression in breast cancer
,Kulkarni, RP;Elmi, A;Alcantara-Adap, E;Hubrack, S;Nader, N;Yu, F;Dib, M;Ramachandran, V;Najafi Shoushtari, H;Machaca, K;,
Sci Rep
,PubMed ID 31506588
[AGO2]
|
MicroRNA therapeutics: design of single-stranded miR-216b mimics to target KRAS in pancreatic cancer cells
,Ferino, A;Miglietta, G;Picco, R;Vogel, S;Wengel, J;Xodo, LE;,
RNA Biol
,PubMed ID 30306823
[AGO2]
|
Novel functional small RNAs are selectively loaded onto mammalian Ago1
,null,
Nucleic Acids Research
,PubMed ID 24627180
[AGO2]
|
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