DUSP13 Human shRNA Plasmid Kit (Locus ID 51207)

Specifications

Product Data
Product Name	DUSP13 Human shRNA Plasmid Kit (Locus ID 51207)
Locus ID	51207
UniProt ID	Q9UII6
Synonyms	BEDP; DUSP13A; DUSP13B; MDSP; SKRP4; TMDP
Vector	pRS
Format	Retroviral plasmids
Kit Components	DUSP13 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 51207). 5µg purified plasmid DNA per construct 29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq	NM_001007271, NM_001007272, NM_001007273, NM_001007274, NM_001007275, NM_001320842, NM_001320843, NM_016364, NM_016364.1, NM_016364.2, NM_016364.3, NM_001007272.1, NM_001007273.1, NM_001007271.1, NM_001007274.1, NM_001007275.1, BC009778, BC009778.1, NM_001363514, NM_001007273.2, NM_001007272.2, NM_001007271.2
Summary	Members of the protein-tyrosine phosphatase superfamily cooperate with protein kinases to regulate cell proliferation and differentiation. This superfamily is separated into two families based on the substrate that is dephosphorylated. One family, the dual specificity phosphatases (DSPs) acts on both phosphotyrosine and phosphoserine/threonine residues. This gene encodes different but related DSP proteins through the use of non-overlapping open reading frames, alternate splicing, and presumed different transcription promoters. Expression of the distinct proteins from this gene has been found to be tissue specific and the proteins may be involved in postnatal development of specific tissues. A protein encoded by the upstream ORF was found in skeletal muscle, whereas the encoded protein from the downstream ORF was found only in testis. In mouse, a similar pattern of expression was found. Multiple alternatively spliced transcript variants were described, but the full-length sequence of only some were determined. [provided by RefSeq, Jul 2008]
shRNA Design	These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Performance Guaranteed	OriGene guarantees that the sequences in the shRNA expression cassettes are verified to correspond to the target gene with 100% identity. One of the four constructs at minimum are guaranteed to produce 70% or more gene expression knock-down provided a minimum transfection efficiency of 80% is achieved. Western Blot data is recommended over qPCR to evaluate the silencing effect of the shRNA constructs 72 hrs post transfection. To properly assess knockdown, the gene expression level from the included scramble control vector must be used in comparison with the target-specific shRNA transfected samples. For non-conforming shRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the shRNA kit. To arrange for a free replacement with newly designed constructs, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled shRNA control (Western Blot data preferred).

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.