gamma Catenin (JUP) Human shRNA Plasmid Kit (Locus ID 3728)

Specifications

Product Data
Product Name	gamma Catenin (JUP) Human shRNA Plasmid Kit (Locus ID 3728)
Locus ID	3728
UniProt ID	P14923
Synonyms	CTNNG; DP3; DPIII; PDGB; PG; PKGB
Vector	pRS
Format	Retroviral plasmids
Kit Components	JUP - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 3728). 5µg purified plasmid DNA per construct 29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free.
RefSeq	NM_002230, NM_021991, NM_001352773, NM_001352774, NM_001352775, NM_001352776, NM_001352777, NM_002230.1, NM_002230.2, NM_021991.1, NM_021991.2, BC011865, BC011865.2, BC000441, NM_002230.4, NM_021991.3
Summary	This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described. [provided by RefSeq, Jul 2008]
shRNA Design	These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Performance Guaranteed	OriGene guarantees that the sequences in the shRNA expression cassettes are verified to correspond to the target gene with 100% identity. One of the four constructs at minimum are guaranteed to produce 70% or more gene expression knock-down provided a minimum transfection efficiency of 80% is achieved. Western Blot data is recommended over qPCR to evaluate the silencing effect of the shRNA constructs 72 hrs post transfection. To properly assess knockdown, the gene expression level from the included scramble control vector must be used in comparison with the target-specific shRNA transfected samples. For non-conforming shRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the shRNA kit. To arrange for a free replacement with newly designed constructs, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled shRNA control (Western Blot data preferred).

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.