Scrambled shRNA control in pRS shRNA Vector
CAT#: TR30012
29-mer Scrambled shRNA Cassette in pRS Vector, 5 ug
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CNY 2,000.00
货期*
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规格
Cited in 463 publications. |
Product images
Specifications
Product Data | |
Product Name | Scrambled shRNA control in pRS shRNA Vector |
shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
Citations (463)
The use of this RNAi has been cited in the following citations: |
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In vivo induction of activin A-producing alveolar macrophages supports the progression of lung cell carcinoma
,null,
Nature Communications
,PubMed ID 36650150
|
Pax6 limits the competence of developing cerebral cortical cells to respond to inductive intercellular signals.
,null,
PLoS biology
,PubMed ID 36067211
|
Targeting mitochondrial DNA polymerase gamma for selective inhibition of MLH1 deficient colon cancer growth
,null,
PLoS ONE
,PubMed ID 35657956
|
Axonal transport of Hrs is activity dependent and facilitates synaptic vesicle protein degradation
,null,
Life Science Alliance
,PubMed ID 35636965
|
ETS variant transcription factor 6 enhances oxidized low-density lipoprotein-induced inflammatory response in atherosclerotic macrophages via activating NF-κB signaling
,null,
International Journal of Immunopathology and Pharmacology
,PubMed ID 35306921
|
ELK3 Controls Gastric Cancer Cell Migration and Invasion by Regulating ECM Remodeling-Related Genes
,null,
International Journal of Molecular Sciences
,PubMed ID 35409069
|
Dyrk1b promotes hepatic lipogenesis by bypassing canonical insulin signaling and directly activating mTORC2 in mice
,null,
The Journal of Clinical Investigation
,PubMed ID 34855620
|
CD90 is regulated by notch1 and hallmarks a more aggressive intrahepatic cholangiocarcinoma phenotype
,null,
Journal of Experimental & Clinical Cancer Research : CR
,PubMed ID 35172861
|
Effective targeting of breast cancer stem cells by combined inhibition of Sam68 and Rad51
,null,
Oncogene
,PubMed ID 35217791
|
Grainyhead 1 acts as a drug-inducible conserved transcriptional regulator linked to insulin signaling and lifespan
,null,
Nature Communications
,PubMed ID 35013237
|
Immunomodulatory Properties of Polysaccharides from the Coral Pseudopterogorgia americana in Macrophages
,null,
Cells
,PubMed ID 34944043
|
MPS1 is involved in the HPV16-E7-mediated centrosomes amplification
,null,
Cell Division
,PubMed ID 34736484
|
Insulin-like Growth Factor Binding Protein-2 (IGFBP2) Is a Key Molecule in the MACC1-Mediated Platelet Communication and Metastasis of Colorectal Cancer Cells
,null,
International Journal of Molecular Sciences
,PubMed ID 34830078
|
HK2 Is a Crucial Downstream Regulator of miR-148a for the Maintenance of Sphere-Forming Property and Cisplatin Resistance in Cervical Cancer Cells
,null,
Frontiers in Oncology
,PubMed ID 34858863
|
A C. elegans model of C9orf72-associated ALS/FTD uncovers a conserved role for eIF2D in RAN translation
,null,
Nature Communications
,PubMed ID 34654821
|
Heterogeneity of subsets in glioblastoma mediated by Smad3 palmitoylation
,null,
Oncogenesis
,PubMed ID 34707087
|
THOC2 and THOC5 Regulate Stemness and Radioresistance in Triple‐Negative Breast Cancer, THOC2 and THOC5 Regulate Stemness and Radioresistance in Triple‐Negative Breast Cancer
,null,
Advanced Science
,PubMed ID 34708581
|
Integrative Network Analysis Revealed Genetic Impact of Pyruvate Kinase L/R on Hepatocyte Proliferation and Graft Survival after Liver Transplantation
,null,
Oxidative Medicine and Cellular Longevity
,PubMed ID 34512869
|
Amplification of DDR2 mediates sorafenib resistance through NF‐κB/c‐Rel signaling in hepatocellular carcinoma
,null,
Cell Biology International
,PubMed ID 33969575
|
Targeting SIRT2 Sensitizes Melanoma Cells to Cisplatin via an EGFR-Dependent Mechanism
,Karwaciak, I;Sałkowska, A;Karaś, K;Dastych, J;Ratajewski, M;,
International Journal of Molecular Sciences
,PubMed ID 34068624
[Scrambled Control ]
|
CircRNA hsa_circ_0006215 promotes osteogenic differentiation of BMSCs and enhances osteogenesis–angiogenesis coupling by competitively binding to miR-942-5p and regulating RUNX2 and VEGF
,null,
Aging (Albany NY)
,PubMed ID 33819188
|
Aminopeptidase A contributes to biochemical, anatomical and cognitive defects in Alzheimer’s disease (AD) mouse model and is increased at early stage in sporadic AD brain
,null,
Acta Neuropathologica
,PubMed ID 33881611
|
DIAPH3 deficiency links microtubules to mitotic errors, defective neurogenesis, and brain dysfunction
,null,
eLife
,PubMed ID 33899739
|
Engineered exosomes delivering specific tumor-suppressive RNAi attenuate oral cancer progression
,Kase, Y;Uzawa, K;Wagai, S;Yoshimura, S;Yamamoto, JI;Toeda, Y;Okubo, M;Eizuka, K;Ando, T;Nobuchi, T;Kawasaki, K;Saito, T;Iyoda, M;Nakashima, D;Kasamatsu, A;Tanzawa, H;,
Scientific reports
,PubMed ID 33723306
[Scrambled Control]
|
The multifunctional role of SPANX-A/D protein subfamily in the promotion of pro-tumoural processes in human melanoma
,null,
Scientific Reports
,PubMed ID 33574425
|
LncRNA DANCR represses Doxorubicin-induced apoptosis through stabilizing MALAT1 expression in colorectal cancer cells
,null,
Cell Death & Disease
,PubMed ID 33414433
|
Hypoxia-Induced S100A8 Expression Activates Microglial Inflammation and Promotes Neuronal Apoptosis
,null,
International Journal of Molecular Sciences
,PubMed ID 33530496
|
Elevated GCN5 expression confers tamoxifen resistance by upregulating AIB1 expression in ER-positive breast cancer
,null,
Cancer Letters
,PubMed ID 32987137
|
Baicalin ameliorates atherosclerosis by inhibiting NLRP3 inflammasome in apolipoprotein E-deficient mice
,null,
Diabetes & Vascular Disease Research
,PubMed ID 33269624
|
Chloroquine reverses chemoresistance via upregulation of p21WAF1/CIP1 and autophagy inhibition in ovarian cancer
,null,
Cell Death & Disease
,PubMed ID 33277461
|
Atractylenolide-I Suppresses Tumorigenesis of Breast Cancer by Inhibiting Toll-Like Receptor 4-Mediated Nuclear Factor-κB Signaling Pathway
,null,
Frontiers in Pharmacology
,PubMed ID 33363472
|
DUSP9-mediated reduction of pERK1/2 supports cancer stem cell-like traits and promotes triple negative breast cancer
,null,
American Journal of Cancer Research
,PubMed ID 33163285
|
Serine 897 Phosphorylation of EPHA2 Is Involved in Signaling of Oncogenic ERK1/2 Drivers in Thyroid Cancer Cells.
,null,
Thyroid : official journal of the American Thyroid Association
,PubMed ID 32762307
|
ROR2 blockade as a therapy for osteoarthritis
,null,
Science Translational Medicine
,PubMed ID 32938794
|
Matrin-3 plays an important role in cell cycle and apoptosis for survival in malignant melanoma.
,null,
Journal of dermatological science
,PubMed ID 32943284
|
Glutathionylated and Fe–S cluster containing hMIA40 (CHCHD4) regulates ROS and mitochondrial complex III and IV activities of the electron transport chain
,null,
Redox Biology
,PubMed ID 32971361
|
UDP-glucose, a cellular danger signal, and nucleotide receptor P2Y14 enhance the invasion of human extravillous trophoblast cells.
,null,
Placenta
,PubMed ID 33011563
|
LY6E Restricts Entry of Human Coronaviruses, Including Currently Pandemic SARS-CoV-2
,null,
Journal of Virology
,PubMed ID 32641482
|
BMP signaling is required for postnatal murine hematopoietic stem cell self-renewal
,null,
Haematologica
,PubMed ID 32675226
|
Progesterone receptor membrane component 1 promotes the growth of breast cancers by altering the phosphoproteome and augmenting EGFR/PI3K/AKT signalling
,null,
British Journal of Cancer
,PubMed ID 32704174
|
Role of zinc transporter ZIP12 in susceptibility-weighted brain magnetic resonance imaging (MRI) phenotypes and mitochondrial function.
,null,
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
,PubMed ID 32716562
|
Epigenetic Reprogramming of Cancer-Associated Fibroblasts Deregulates Glucose Metabolism and Facilitates Progression of Breast Cancer
,null,
Cell reports
,PubMed ID 32492417
|
Ribosome collisions trigger general stress responses to regulate cell fate
,null,
Cell
,PubMed ID 32610081
|
The focal adhesion protein kindlin-2 controls mitotic spindle assembly by inhibiting histone deacetylase 6 and maintaining α-tubulin acetylation
,null,
The Journal of Biological Chemistry
,PubMed ID 32169902
|
Free fatty acids receptors 2 and 3 control cell proliferation by regulating cellular glucose uptake
,null,
World Journal of Gastrointestinal Oncology
,PubMed ID 32461783
|
Heat shock protein 47 promotes tumor survival and therapy resistance by modulating AKT signaling via PHLPP1 in colorectal cancer
,null,
Cancer Biology & Medicine
,PubMed ID 32587773
|
Polyunsaturated Fatty Acid Desaturation Is a Mechanism for Glycolytic NAD + Recycling
,null,
Cell metabolism
,PubMed ID 30686744
|
Mechanism of miR-222 and miR-126 regulation and its role in asbestos-induced malignancy
,Gaetani, S;Monaco, F;Alessandrini, F;Tagliabracci, A;Sabbatini, A;Bracci, M;Valentino, M;Neuzil, J;Amati, M;Santarelli, L;Tomasetti, M;,
Int. J. Biochem. Cell Biol.
,PubMed ID 32006662
[negative Control]
|
Acid/bile exposure triggers TRAIL-mediated apoptosis in esophageal cancer cells by suppressing the decoy receptors and c-FLIPR
,Meng, X;Chang, Z;Che, N;Wu, J;Dang, T;Chai, J;,
The International Journal of Biochemistry & Cell Biology
,PubMed ID 32135301
[negative Control]
|
Ecm29-mediated proteasomal distribution modulates excitatory GABA responses in the developing brain
,null,
The Journal of Cell Biology
,PubMed ID 31910261
|
Potentiation of cancerous progression by LISCH7 via direct stimulation of TGFB1 transcription in triple-negative breast cancer.
,null,
Journal of cellular biochemistry
,PubMed ID 32048750
|
Heat Shock Protein 47 Maintains Cancer Cell Growth by Inhibiting the Unfolded Protein Response Transducer IRE1α.
,null,
Molecular cancer research : MCR
,PubMed ID 32102897
|
Exercise Training-Induced PPARβ Increases PGC-1α Protein Stability and Improves Insulin-Induced Glucose Uptake in Rodent Muscles
,null,
Nutrients
,PubMed ID 32121211
|
CoA Synthase (COASY) mediates radiation resistance via PI3K signaling in rectal cancer
,null,
Cancer research
,PubMed ID 31704889
|
Allergin-1 Immunoreceptor Suppresses House Dust Mite-Induced Allergic Airway Inflammation.
,null,
Journal of immunology (Baltimore, Md. : 1950)
,PubMed ID 31900344
|
Host Wnt5a Potentiates Microenvironmental Regulation of Ovarian Cancer Metastasis
,null,
Cancer research
,PubMed ID 31932454
|
STIM Protein-NMDA2 Receptor Interaction Decreases NMDA-Dependent Calcium Levels in Cortical Neurons
,null,
Cells
,PubMed ID 31936514
|
Activation of JNK and p38 MAPK Mediated by ZDHHC17 Drives Glioblastoma Multiforme Development and Malignant Progression
,null,
Theranostics
,PubMed ID 31938047
|
CXCL12-induced rescue of cortical dendritic spines and cognitive flexibility
,null,
eLife
,PubMed ID 31971513
|
Biallelic DMXL2 mutations impair autophagy and cause Ohtahara syndrome with progressive course.
,null,
Brain : a journal of neurology
,PubMed ID 31688942
|
Modulation of CXC-motif chemokine receptor 7, but not 4, expression is related to migration of the human prostate cancer cell LNCaP: regulation by androgen and inflammatory stimuli.
,null,
Inflammation research : official journal of the European Histamine Research Society ... [et al.]
,PubMed ID 31865399
|
Upregulation of musashi1 increases malignancy of hepatocellular carcinoma via the Wnt/β-catenin signaling pathway and predicts a poor prognosis
,null,
BMC Gastroenterology
,PubMed ID 31888604
|
Redistribution of EC-SOD resolves bleomycin-induced inflammation via increased apoptosis of recruited alveolar macrophages
,null,
The FASEB Journal
,PubMed ID 31560857
|
Fc Receptor-Like 1 as a Promising Target for Immunotherapeutic Interventions of B-Cell-Related Disorders
,null,
Biomarker Insights
,PubMed ID 31798301
|
MAPKAP kinase 2–mediated phosphorylation of HspA1L protects male germ cells from heat stress–induced apoptosis
,null,
Cell Stress & Chaperones
,PubMed ID 31642047
|
Distinct Signaling Pathways Regulate TREM2 Phagocytic and NFκB Antagonistic Activities
,null,
Frontiers in Cellular Neuroscience
,PubMed ID 31649511
|
Lymphocyte-Specific Protein-1 Controls Sorafenib Sensitivity and Hepatocellular Proliferation through Extracellular Signal-Regulated Kinase 1/2 Activation
,null,
The American Journal of Pathology
,PubMed ID 30126548
|
Spleen tyrosine kinase (SYK) blocks autophagic Tau degradation in vitro and in vivo
,null,
The Journal of Biological Chemistry
,PubMed ID 31324720
|
Inflammatory Micro-environment Contributes to Stemness Properties and Metastatic Potential of HCC via the NF-κB/miR-497/SALL4 Axis
,null,
Molecular Therapy Oncolytics
,PubMed ID 31650028
|
Oncogenic splicing abnormalities induced by DEAD‐Box Helicase 56 amplification in colorectal cancer, et al. Oncogenic splicing abnormalities induced by DEAD‐Box Helicase 56 amplification in colorectal cancer
,null,
Cancer Science
,PubMed ID 31390121
|
Analysis of head and neck carcinoma progression reveals novel and relevant stage-specific changes associated with immortalisation and malignancy
,null,
Scientific Reports
,PubMed ID 31427592
|
α-Fodrin is required for the organization of functional microtubules during mitosis
,null,
Cell Cycle
,PubMed ID 31455186
|
Platelet-rich plasma activates AKT signaling to promote wound healing in a mouse model of radiation-induced skin injury
,null,
Journal of Translational Medicine
,PubMed ID 31462256
|
PINK1 depletion sensitizes non-small cell lung cancer to glycolytic inhibitor 3-bromopyruvate: Involvement of ROS and mitophagy.
,null,
Pharmacological reports : PR
,PubMed ID 31669882
|
Targeting Interleukin(IL)-30/IL-27p28 signaling in cancer stem-like cells and host environment synergistically inhibits prostate cancer growth and improves survival
,null,
Journal for Immunotherapy of Cancer
,PubMed ID 31366386
|
BCDIN3D regulates tRNAHis 3' fragment processing
,Reinsborough, CW;Ipas, H;Abell, NS;Nottingham, RM;Yao, J;Devanathan, SK;Shelton, SB;Lambowitz, AM;Xhemalçe, B;,
PLoS Genet.
,PubMed ID 31329584
[Negative Control]
|
Gasdermin D protects against noninfectious liver injury by regulating apoptosis and necroptosis
,null,
Cell Death & Disease
,PubMed ID 31209224
|
SIRT2 Contributes to the Resistance of Melanoma Cells to the Multikinase Inhibitor Dasatinib
,Karwaciak, I;Sałkowska, A;Karaś, K;Sobalska-Kwapis, M;Walczak-Drzewiecka, A;Pułaski, Ł;Strapagiel, D;Dastych, J;Ratajewski, M;,
Cancers (Basel) 2019
,PubMed ID 31091806
[Negative Control]
|
Mitochondrial protein 18 is a positive apoptotic regulator in cardiomyocytes under oxidative stress.
,null,
Clinical science (London, England : 1979)
,PubMed ID 31015359
|
Spastin Contributes to Neural Development through the Regulation of Microtubule Dynamics in the Primary Cilia of Neural Stem Cells.
,null,
Neuroscience
,PubMed ID 31150727
|
c-MYB- and PGC1a-dependent metabolic switch induced by MYBBP1A loss in renal cancer
,Felipe-Abrio, B;Verdugo-Sivianes, EM;Carnero, A;,
Mol Oncol
,PubMed ID 31066170
[Negative Control]
|
HDAC8 regulates a stress response pathway in melanoma to mediate escape from BRAF inhibitor therapy
,null,
Cancer research
,PubMed ID 30987999
|
Silencing Y-box binding protein-1 inhibits triple-negative breast cancer cell invasiveness via regulation of MMP1 and beta-catenin expression.
,null,
Cancer letters
,PubMed ID 30905819
|
Network approach identifies Pacer as an autophagy protein involved in ALS pathogenesis
,null,
Molecular Neurodegeneration
,PubMed ID 30917850
|
Wnt1 silences chemokine genes in dendritic cells and induces adaptive immune resistance in lung adenocarcinoma
,null,
Nature Communications
,PubMed ID 30926812
|
Neural EGFL-Like 1 Regulates Cartilage Maturation through Runt-Related Transcription Factor 3–Mediated Indian Hedgehog Signaling
,null,
The American Journal of Pathology
,PubMed ID 29137952
|
LINC00261 is an epigenetically-regulated tumor suppressor essential for activation of the DNA damage response
,null,
Cancer research
,PubMed ID 30796052
|
High expression of RAD18 in glioma induces radiotherapy resistance via down-regulating P53 expression.
,null,
Biomedicine pharmacotherapy = Biomedecine pharmacotherapie
,PubMed ID 30798132
|
Knockdown of Orphan Transporter SLC22A18 Impairs Lipid Metabolism and Increases Invasiveness of HepG2 Cells
,Ito, S;Honda, G;Fujino, Y;Ogata, S;Hirayama-Kurogi, M;Ohtsuki, S;,
Pharm. Res.
,PubMed ID 30635741
[Negative Control]
|
KLF14 potentiates oxidative adaptation via modulating HO-1 signaling in castrate-resistant prostate cancer.
,null,
Endocrine-related cancer
,PubMed ID 30400002
|
TFAP2C- and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage Commitment
,null,
Cell stem cell
,PubMed ID 30686763
|
Monoclonal Antibody against CXCL1 (HL2401) as a Novel Agent in Suppressing IL6 Expression and Tumoral Growth
,null,
Theranostics
,PubMed ID 30809313
|
Oncogenic transgelin-2 is differentially regulated in isocitrate dehydrogenase wild-type vs. mutant gliomas
,null,
Oncotarget
,PubMed ID 30647847
|
Down-regulation of 14-3-3 zeta sensitizes human glioblastoma cells to apoptosis induction.
,null,
Apoptosis : an international journal on programmed cell death
,PubMed ID 30101359
|
Coincidence Detection of Membrane Stretch and Extracellular pH by the Proton-Sensing Receptor OGR1 (GPR68)
,null,
Current Biology
,PubMed ID 30471999
|
Islr regulates canonical Wnt signaling-mediated skeletal muscle regeneration by stabilizing Dishevelled-2 and preventing autophagy
,null,
Nature Communications
,PubMed ID 30510196
|
(Pro)renin receptor promotes colorectal cancer through the Wnt/beta-catenin signalling pathway despite constitutive pathway component mutations
,null,
British Journal of Cancer
,PubMed ID 30555158
|
Poly(ADP-ribose) polymerase 1 is necessary for coactivating hypoxia-inducible factor-1-dependent gene expression by Epstein-Barr virus latent membrane protein 1
,null,
PLoS Pathogens
,PubMed ID 30395643
|
Role of a TRIM72 ADP-ribosylation cycle in myocardial injury and membrane repair
,null,
JCI Insight
,PubMed ID 30429362
|
Mast Cell CRF2 Suppresses Mast Cell Degranulation and Limits the Severity of Anaphylaxis and Stress-Induced Intestinal Permeability
,null,
The Journal of allergy and clinical immunology
,PubMed ID 30439403
|
Hypovitaminosis D exacerbates the DNA damage load in human uterine fibroids, which is ameliorated by vitamin D3 treatment
,null,
Acta Pharmacologica Sinica
,PubMed ID 30478352
|
Fra-2 Expression in Osteoblasts Regulates Systemic Inflammation and Lung Injury through Osteopontin
,null,
Molecular and Cellular Biology
,PubMed ID 30181393
|
(-)‑Oleocanthal inhibits proliferation and migration by modulating Ca2+ entry through TRPC6 in breast cancer cells.
,null,
Biochimica et biophysica acta. Molecular cell research
,PubMed ID 30321616
|
Myoferlin-Mediated Lysosomal Exocytosis Regulates Cytotoxicity by Phagocytes.
,null,
Journal of immunology (Baltimore, Md. : 1950)
,PubMed ID 30333125
|
Quiescin Sulfhydryl Oxidase 1 (QSOX1) Secreted by Lung Cancer Cells Promotes Cancer Metastasis
,null,
International Journal of Molecular Sciences
,PubMed ID 30336636
|
Chronic Cigarette Smoke-Induced Epigenomic Changes Precede Sensitization of Bronchial Epithelial Cells to Single Step Transformation by KRAS Mutations
,null,
Cancer cell
,PubMed ID 28898697
|
Rasip1 controls lymphatic vessel lumen maintenance by regulating endothelial cell junctions
,null,
Development (Cambridge, England)
,PubMed ID 30042182
|
TRPC6 Channels Are Required for Proliferation, Migration and Invasion of Breast Cancer Cell Lines by Modulation of Orai1 and Orai3 Surface Exposure
,null,
Cancers
,PubMed ID 30223530
|
GLI3 knockdown decreases stemness, cell proliferation and invasion in oral squamous cell carcinoma
,null,
International Journal of Oncology
,PubMed ID 30272273
|
WNT6 is a novel oncogenic prognostic biomarker in human glioblastoma
,Gonçalves, C;de Castro, J;Pojo, M;Martins, E;Queirós, S;Chautard, E;Taipa, R;Pires, M;Pinto, A;Pardal, F;Custódia, C;Faria, C;Clara, C;Reis, R;Sousa, N;Costa, B;,
Theranostics
,PubMed ID 30279739
[Negative Control]
|
Involvement of an orphan transporter, SLC22A18, in cell growth and drug resistance of human breast cancer MCF7 cells
,Ito, S;Fujino, Y;Ogata, S;Hirayama-Kurogi, M;Ohtsuki, S;,
J Pharm Sci
,PubMed ID 30145211
[Negative Control]
|
Melatonin and 5-fluorouracil co-suppress colon cancer stem cells by regulating cellular prion protein-Oct4 axis.
,null,
Journal of pineal research
,PubMed ID 30091203
|
APOBEC3 Mediates Resistance to Oncolytic Viral Therapy
,null,
Molecular Therapy Oncolytics
,PubMed ID 30294666
|
N-Linked Glycosylation Is Not Essential for Sodium Taurocholate Cotransporting Polypeptide To Mediate Hepatitis B Virus Infection In Vitro
,null,
Journal of Virology
,PubMed ID 29793953
|
Procyanidin B2 protects rats from paraquat-induced acute lung injury by inhibiting NLRP3 inflammasome activation.
,null,
Immunobiology
,PubMed ID 30025709
|
Extracellular vesicles with altered tetraspanin CD9 and CD151 levels confer increased prostate cell motility and invasion
,null,
Scientific Reports
,PubMed ID 29891991
|
Peroxiredoxin 1 protein interacts with influenza virus ribonucleoproteins and is required for efficient virus replication.
,null,
Vaccine
,PubMed ID 29921490
|
Integrated transcriptomic and epigenomic analysis of ovarian cancer reveals epigenetically silenced GULP1.
,null,
Cancer letters
,PubMed ID 29964205
|
UPF1 silenced cellular model systems for screening of read-through agents active on β039 thalassemia point mutation
,null,
BMC Biotechnology
,PubMed ID 29764417
|
Wnt signal activation induces midbrain specification through direct binding of the beta-catenin/TCF4 complex to the EN1 promoter in human pluripotent stem cells
,null,
Experimental & Molecular Medicine
,PubMed ID 29650976
|
CADM1 is essential for KSHV-encoded vGPCR-and vFLIP-mediated chronic NF-κB activation
,null,
PLoS Pathogens
,PubMed ID 29698475
|
αvβ5 integrin mediates the effect of vitronectin on the initial stage of differentiation in mouse cerebellar granule cell precursors.
,null,
Brain research
,PubMed ID 29702083
|
Reduced mannosidase MAN1A1 expression leads to aberrant N-glycosylation and impaired survival in breast cancer
,null,
British Journal of Cancer
,PubMed ID 29381688
|
Tumor-Repopulating Cells Induce PD-1 Expression in CD8+ T Cells by Transferring Kynurenine and AhR Activation.
,null,
Cancer cell
,PubMed ID 29533786
|
SOX9 Transcriptionally Regulates mTOR-Induced Proliferation of Basal Cell Carcinomas
,null,
The Journal of investigative dermatology
,PubMed ID 29550418
|
Transmembrane TNF-alpha promotes chemoresistance in breast cancer cells
,null,
Oncogene
,PubMed ID 29559745
|
Secretion-mediated STAT3 activation promotes self-renewal of glioma stem-like cells during hypoxia
,null,
Oncogene
,PubMed ID 29155422
|
HDAC6 is a therapeutic target in mutant GARS-induced Charcot-Marie-Tooth disease
,null,
Brain
,PubMed ID 29415205
|
Targeting Tyro3 ameliorates a model of PGRN-mutant FTLD-TDP via tau-mediated synaptic pathology
,Fujita, K;Chen, X;Homma, H;Tagawa, K;Amano, M;Saito, A;Imoto, S;Akatsu, H;Hashizume, Y;Kaibuchi, K;Miyano, S;Okazawa, H;,
Nat Commun
,PubMed ID 29382817
[Scrambled shRNA]
|
Nfatc1 Is a Functional Transcriptional Factor Mediating Nell-1-Induced Runx3 Upregulation in Chondrocytes
,null,
International Journal of Molecular Sciences
,PubMed ID 29316655
|
Noxa/HSP27 Complex Delays Degradation of Ubiquitylated IkBα in Airway Epithelial Cells to Reduce Pulmonary Inflammation
,null,
Mucosal immunology
,PubMed ID 29363670
|
SALL1 expression in acute myeloid leukemia
,null,
Oncotarget
,PubMed ID 29484122
|
Ginsenoside-Rg1 Protects against Renal Fibrosis by Regulating the Klotho/TGF-β1/Smad Signaling Pathway in Rats with Obstructive Nephropathy.
,null,
Biological pharmaceutical bulletin
,PubMed ID 29607931
|
The perlecan-interacting growth factor progranulin regulates ubiquitination, sorting, and lysosomal degradation of sortilin
,null,
Matrix biology : journal of the International Society for Matrix Biology
,PubMed ID 28433812
|
Paxillin facilitates timely neurite initiation on soft-substrate environments by interacting with the endocytic machinery
,null,
eLife
,PubMed ID 29271742
|
Brain insulin resistance impairs hippocampal synaptic plasticity and memory by increasing GluA1 palmitoylation through FoxO3a
,null,
Nature Communications
,PubMed ID 29222408
|
Hypoxia-induced upregulation of BMX kinase mediates therapeutic resistance in acute myeloid leukemia
,null,
The Journal of Clinical Investigation
,PubMed ID 29227282
|
Klotho upregulation contributes to the neuroprotection of ligustilide against cerebral ischemic injury in mice.
,null,
European journal of pharmacology
,PubMed ID 29233659
|
Evaluation of tryptophan-aspartic acid repeat-containing protein 34 as a novel tumor-suppressor molecule in human oral cancer
,Yamamoto, JI;Kasamatsu, A;Okubo, Y;Nakashima, D;Fushimi, K;Minakawa, Y;Kasama, H;Shiiba, M;Tanzawa, H;Uzawa, K;,
Biochem. Biophys. Res. Commun.
,PubMed ID 29278705
[Non-effective Control]
|
Downregulation of Bit1 expression promotes growth, anoikis resistance, and transformation of immortalized human bronchial epithelial cells via Erk activation-dependent suppression of E-cadherin
,null,
Biochemical and biophysical research communications
,PubMed ID 29170133
|
TNF-α receptor 1 knockdown in the subfornical organ ameliorates sympathetic excitation and cardiac hemodynamics in heart failure rats
,null,
American Journal of Physiology - Heart and Circulatory Physiology
,PubMed ID 28710070
|
HIV-1 viral protein R (Vpr) induces fatty liver in mice via LXRα and PPARα dysregulation: implications for HIV-specific pathogenesis of NAFLD
,null,
Scientific Reports
,PubMed ID 29042644
|
iASPP facilitates tumor growth by promoting mTOR-dependent autophagy in human non-small-cell lung cancer
,null,
Cell Death & Disease
,PubMed ID 29072696
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Endoplasmic reticulum oxidase 1α is critical for collagen secretion from and membrane type 1-matrix metalloproteinase levels in hepatic stellate cells
,null,
The Journal of Biological Chemistry
,PubMed ID 28774960
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A large-scale RNAi screen identifies LCMR1 as a critical regulator of Tspan8-mediated melanoma invasion.
,null,
Oncogene
,PubMed ID 27375018
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Comparative global immune-related gene profiling of somatic cells, human pluripotent stem cells and their derivatives: implication for human lymphocyte proliferation
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Experimental & Molecular Medicine
,PubMed ID 28912571
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Pancreatic β-Cell–Derived IP-10/CXCL10 Isletokine Mediates Early Loss of Graft Function in Islet Cell Transplantation
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Diabetes
,PubMed ID 28855240
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Deletion of the Vaccinia Virus B1 Kinase Reveals Essential Functions of This Enzyme Complemented Partly by the Homologous Cellular Kinase VRK2
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Journal of Virology
,PubMed ID 28515294
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Functional expression of calcium‐permeable canonical transient receptor potential 4‐containing channels promotes migration of medulloblastoma cells
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The Journal of Physiology
,PubMed ID 28627017
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Avian reovirus p17 and σA act cooperatively to downregulate Akt by suppressing mTORC2 and CDK2/cyclin A2 and upregulating proteasome PSMB6
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Scientific Reports
,PubMed ID 28701787
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DNA methylation protects against cisplatin-induced kidney injury by regulating specific genes including interferon regulatory factor 8
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Kidney international
,PubMed ID 28709638
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Nrf2 deficiency exacerbates ochratoxin A-induced toxicity in vitro and in vivo.
,null,
Toxicology
,PubMed ID 28710020
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Microbubble-based enhancement of radiation effect: Role of cell membrane ceramide metabolism
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PLoS ONE
,PubMed ID 28746357
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Knockdown of Mtfp1 can minimize doxorubicin cardiotoxicity by inhibiting Dnm1l‐mediated mitochondrial fission
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Journal of Cellular and Molecular Medicine
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MARK4 regulates NLRP3 positioning and inflammasome activation through a microtubule-dependent mechanism
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Nature Communications
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SIRT1 Regulates the Chemoresistance and Invasiveness of Ovarian Carcinoma Cells
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Translational Oncology
,PubMed ID 28667895
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FOXD3 regulates anaplastic thyroid cancer progression
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Oncotarget
,PubMed ID 28430585
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CXCR7 maintains osteosarcoma invasion after CXCR4 suppression in bone marrow microenvironment.
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Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
,PubMed ID 28468584
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Blockade of IDO-kynurenine-AhR metabolic circuitry abrogates IFN-γ-induced immunologic dormancy of tumor-repopulating cells
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Nature Communications
,PubMed ID 28488695
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Fibulin-3 promotes muscle-invasive bladder cancer.
,null,
Oncogene
,PubMed ID 28504717
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Netrin‐1 Preserves Blood‐Brain Barrier Integrity Through Deleted in Colorectal Cancer/Focal Adhesion Kinase/RhoA Signaling Pathway Following Subarachnoid Hemorrhage in Rats
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Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
,PubMed ID 28526701
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Expression of tripartite motif-containing protein 28 in primary breast carcinoma predicts metastasis and is involved in the stemness, chemoresistance, and tumor growth.
,null,
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
,PubMed ID 28381187
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Promoter hypermethylation as a mechanism for Lamin A/C silencing in a subset of neuroblastoma cells
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PLoS ONE
,PubMed ID 28422997
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Novel SUMO-Protease SENP7S Regulates β-catenin Signaling and Mammary Epithelial Cell Transformation
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Scientific Reports
,PubMed ID 28429743
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MicroRNA-375 Is Induced in Cisplatin Nephrotoxicity to Repress Hepatocyte Nuclear Factor 1-β *
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The Journal of Biological Chemistry
,PubMed ID 28119452
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PNPLA1 is a transacylase essential for the generation of the skin barrier lipid ω-O-acylceramide
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Nature Communications
,PubMed ID 28248318
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Ten-Eleven Translocation-2 (Tet2) Is Involved in Myogenic Differentiation of Skeletal Myoblast Cells in Vitro
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Scientific Reports
,PubMed ID 28272491
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Mesothelin promotes epithelial-to-mesenchymal transition and tumorigenicity of human lung cancer and mesothelioma cells
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Molecular Cancer
,PubMed ID 28288645
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FOXO1 Suppression is a Determinant of Acquired Lapatinib-Resistance in HER2-Positive Gastric Cancer Cells Through MET Upregulation
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Cancer Research and Treatment : Official Journal of Korean Cancer Association
,PubMed ID 28343375
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Decreased RNA-binding motif 5 expression is associated with tumor progression in gastric cancer.
,null,
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
,PubMed ID 28347247
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Targeting Smoothened Sensitizes Gastric Cancer to Chemotherapy in Experimental Models
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Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
,PubMed ID 28350784
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Fibronectin 1 promotes migration and invasion of papillary thyroid cancer and predicts papillary thyroid cancer lymph node metastasis
,null,
OncoTargets and therapy
,PubMed ID 28367057
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Interleukin-37 suppresses the osteogenic responses of human aortic valve interstitial cells in vitro and alleviates valve lesions in mice
,null,
Proceedings of the National Academy of Sciences of the United States of America
,PubMed ID 28137840
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NF-κB regulates neuronal ankyrin-G via a negative feedback loop
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Scientific Reports
,PubMed ID 28181483
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Astrocyte-induced Reelin expression drives proliferation of Her2+ breast cancer metastases
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Clinical & experimental metastasis
,PubMed ID 28210910
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Hyperglycemia-Induced Changes in ZIP7 and ZnT7 Expression Cause Zn2+ Release From the Sarco(endo)plasmic Reticulum and Mediate ER Stress in the Heart.
,null,
Diabetes
,PubMed ID 28232492
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ADAR1 restricts LINE-1 retrotransposition
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Nucleic Acids Research
,PubMed ID 27658966
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Tbx20 controls the expression of the KCNH2 gene and of hERG channels
,null,
Proceedings of the National Academy of Sciences of the United States of America
,PubMed ID 28049825
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PRMT2 interacts with splicing factors and regulates the alternative splicing of BCL-X
,null,
Journal of Biochemistry
,PubMed ID 28057797
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Isoform-specific subcellular localization and function of protein kinase A identified by mosaic imaging of mouse brain
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eLife
,PubMed ID 28079521
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MicroRNA-141 enhances anoikis resistance in metastatic progression of ovarian cancer through targeting KLF12/Sp1/survivin axis
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Molecular Cancer
,PubMed ID 28095864
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CK2 abrogates the inhibitory effects of PRH/HHEX on prostate cancer cell migration and invasion and acts through PRH to control cell proliferation
,null,
Oncogenesis
,PubMed ID 28134934
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Gata6 promotes hair follicle progenitor cell renewal by genome maintenance during proliferation
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The EMBO Journal
,PubMed ID 27908934
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Emergent Role of the Fractalkine Axis in Dissemination of Peritoneal Metastasis from Epithelial Ovarian Carcinoma
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Oncogene
,PubMed ID 27941884
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CD44-shRNA recombinant adenovirus inhibits cell proliferation, invasion, and migration, and promotes apoptosis in HCT116 colon cancer cells.
,null,
International journal of oncology
,PubMed ID 27959393
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Dynamic Partitioning of Synaptic Vesicle Pools by the SNARE-Binding Protein Tomosyn
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The Journal of Neuroscience
,PubMed ID 27807164
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Autophagy Induction Results in Enhanced Anoikis-resistance in Models of Peritoneal Disease
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Molecular cancer research : MCR
,PubMed ID 27807188
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FOXP1 is a regulator of quiescence in healthy human CD4+ T cells and is constitutively repressed in T cells from patients with lymphoproliferative disorders.
,null,
European journal of immunology
,PubMed ID 27861791
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Survivin inhibitor YM155 induces mitochondrial dysfunction, autophagy, DNA damage and apoptosis in BclxL silenced glioma cell lines
,Jane, EP;Premkumar, DR;Sutera, PA;Cavaleri, JM;Pollack, IF;,
Molecular carcinogenesis
,PubMed ID 27805285
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MicroRNA 10b promotes abnormal expression of the proto-oncogene c-Jun in metastatic breast cancer cells
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Oncotarget
,PubMed ID 27494896
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Adrenomedullin2 (ADM2)/Intermedin (IMD): A Potential Role in the Pathophysiology of Preeclampsia
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The Journal of Clinical Endocrinology and Metabolism
,PubMed ID 27583470
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ATM Expression Predicts Veliparib and Irinotecan Sensitivity in Gastric Cancer by Mediating P53-Independent Regulation of Cell Cycle and Apoptosis.
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Molecular cancer therapeutics
,PubMed ID 27638859
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The Anoikis Effector Bit1 Inhibits EMT through Attenuation of TLE1-Mediated Repression of E-Cadherin in Lung Cancer Cells
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PLoS ONE
,PubMed ID 27655370
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Platelet integrin α6 β1 controls lung metastasis through direct binding to cancer cell–derived ADAM9
,null,
JCI Insight
,PubMed ID 27699237
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Glioma-induced inhibition of caspase-3 in microglia promotes a tumor-supportive phenotype
,Shen, X;Burguillos, MA;Osman, AM;Frijhoff, J;Carrillo-Jiménez, A;Kanatani, S;Augsten, M;Saidi, D;Rodhe, J;Kavanagh, E;Rongvaux, A;Rraklli, V;Nyman, U;Holmberg, J;Östman, A;Flavell, RA;Barragan, A;Venero, JL;Blomgren, K;Joseph, B;,
Nat. Immunol.
,PubMed ID 27618552
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Phosphorylation of the RNA-binding protein Dazl by MAPKAP kinase 2 regulates spermatogenesis
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Molecular Biology of the Cell
,PubMed ID 27280388
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The dual role of asporin in breast cancer progression
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Oncotarget
,PubMed ID 27409832
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Suppression of CEP55 reduces cell viability and induces apoptosis in human lung cancer.
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Oncology reports
,PubMed ID 27633074
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IMP2 axonal localization, RNA interactome, and function in the development of axon trajectories
,Preitner, N;Quan, J;Li, X;Nielsen, FC;Flanagan, JG;,
Development
,PubMed ID 27385015
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CREG1 Interacts with Sec8 to Promote Cardiomyogenic Differentiation and Cell-Cell Adhesion.
,null,
Stem cells (Dayton, Ohio)
,PubMed ID 27334848
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Role of mesothelin in carbon nanotube-induced carcinogenic transformation of human bronchial epithelial cells
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American Journal of Physiology - Lung Cellular and Molecular Physiology
,PubMed ID 27422997
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The mitochondrial ubiquitin ligase plays an anti‐apoptotic role in cardiomyocytes by regulating mitochondrial fission
,null,
Journal of Cellular and Molecular Medicine
,PubMed ID 27444773
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PAC down-regulates estrogen receptor alpha and suppresses epithelial-to-mesenchymal transition in breast cancer cells
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BMC Cancer
,PubMed ID 27465411
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Regulation of post-Golgi LH3 trafficking is essential for collagen homeostasis
,Banushi, B;Forneris, F;Straatman-Iwanowska, A;Strange, A;Lyne, AM;Rogerson, C;Burden, JJ;Heywood, WE;Hanley, J;Doykov, I;Straatman, KR;Smith, H;Bem, D;Kriston-Vizi, J;Ariceta, G;Risteli, M;Wang, C;Ardill, RE;Zaniew, M;Latka-Grot, J;Waddington, SN;Howe, SJ;Ferraro, F;Gjinovci, A;Lawrence, S;Marsh, M;Girolami, M;Bozec, L;Mills, K;Gissen, P;,
Nat Commun
,PubMed ID 27435297
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Heterozygous PALB2 c.1592delT mutation channels DNA double-strand break repair into error-prone pathways in breast cancer patients
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Oncogene
,PubMed ID 26640152
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Inhibition of the Expression of the Small Heat Shock Protein αB-Crystallin Inhibits Exosome Secretion in Human Retinal Pigment Epithelial Cells in Culture *
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The Journal of Biological Chemistry
,PubMed ID 27129211
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WDR5 high expression and its effect on tumorigenesis in leukemia
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Oncotarget
,PubMed ID 27192115
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miR-93 regulates Msk2-mediated chromatin remodelling in diabetic nephropathy
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Nature Communications
,PubMed ID 27350436
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Transmembrane Protein 88 (TMEM88) Promoter Hypomethylation is Associated with Platinum Resistance in Ovarian Cancer
,null,
Gynecologic oncology
,PubMed ID 27374141
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Glucocorticoid receptor beta increases migration of human bladder cancer cells
,null,
Oncotarget
,PubMed ID 27036026
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Cyclic Nucleotide Control of Microtubule Dynamics for Axon Guidance
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The Journal of Neuroscience
,PubMed ID 27194341
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Regulation of membrane KCNQ1/KCNE1 channel density by sphingomyelin synthase 1
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American Journal of Physiology - Cell Physiology
,PubMed ID 27194473
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Galectin-1 suppression delineates a new strategy to inhibit myeloma-induced angiogenesis and tumoral growth in vivo.
,null,
Leukemia
,PubMed ID 27311934
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SIRT7 promotes genome integrity and modulates non-homologous end joining DNA repair
,Vazquez, BN;Thackray, JK;Simonet, NG;Kane-Goldsmith, N;Martinez-Redondo, P;Nguyen, T;Bunting, S;Vaquero, A;Tischfield, JA;Serrano, L;,
EMBO J.
,PubMed ID 27225932
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Oncogenic mutations and dysregulated pathways in obesity-associated hepatocellular carcinoma
,Shen, J;Tsoi, H;Liang, Q;Chu, ES;Liu, D;Yu, AC;Chan, TF;Li, X;Sung, JJ;Wong, VW;Yu, J;,
Oncogene
,PubMed ID 27132506
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SIRT2 inhibits non-small cell lung cancer cell growth through impairing Skp2-mediated p27 degradation
,null,
Oncotarget
,PubMed ID 26942878
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Instigation of NLRP3 inflammasome activation and glomerular injury in mice on the high fat diet: role of acid sphingomyelinase gene
,null,
Oncotarget
,PubMed ID 26980705
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ERAP1 Reduces Accumulation of Aberrant and Disulfide-Linked Forms of HLA-B27 on the Cell Surface
,null,
Molecular immunology
,PubMed ID 27107845
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Heparin Decreases in Tumor Necrosis Factor α (TNFα)-induced Endothelial Stress Responses Require Transmembrane Protein 184A and Induction of Dual Specificity Phosphatase 1 *
,null,
The Journal of Biological Chemistry
,PubMed ID 26769965
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Transmembrane Protein 184A Is a Receptor Required for Vascular Smooth Muscle Cell Responses to Heparin *
,null,
The Journal of Biological Chemistry
,PubMed ID 26769966
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A CEP215–HSET complex links centrosomes with spindle poles and drives centrosome clustering in cancer
,null,
Nature Communications
,PubMed ID 26987684
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The RNA-binding protein LARP1 is a post-transcriptional regulator of survival and tumorigenesis in ovarian cancer
,null,
Nucleic Acids Research
,PubMed ID 26717985
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Targeted next-generation sequencing for molecular diagnosis of endometriosis-associated ovarian cancer.
,null,
Journal of molecular medicine (Berlin, Germany)
,PubMed ID 26920370
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miR-30a inhibits endothelin A receptor and chemoresistance in ovarian carcinoma
,null,
Oncotarget
,PubMed ID 26675258
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Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity
,null,
Acta neuropathologica
,PubMed ID 26728149
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Cdx2 Expression and Intestinal Metaplasia Induced by H. pylori Infection of Gastric Cells Is Regulated by NOD1-Mediated Innate Immune Responses
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Cancer research
,PubMed ID 26759244
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Glyoxalase I drives epithelial-to-mesenchymal transition via argpyrimidine-modified Hsp70, miR-21 and SMAD signalling in human bronchial cells BEAS-2B chronically exposed to crystalline silica Min-U-Sil 5: Transformation into a neoplastic-like phenotype.
,null,
Free radical biology medicine
,PubMed ID 26784015
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Ghrelin receptor regulates adipose tissue inflammation in aging
,null,
Aging (Albany NY)
,PubMed ID 26837433
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Involvement of TonEBP/NFAT5 in osmoadaptative response of human retinal pigmented epithelial cells to hyperosmolar stress
,null,
Molecular Vision
,PubMed ID 26912969
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Profiling analysis of protein tyrosine phosphatases during neuronal differentiation.
,null,
Neuroscience letters
,PubMed ID 26704437
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KISS1R signaling promotes invadopodia formation in human breast cancer cell via β-arrestin2/ERK.
,null,
Cellular signalling
,PubMed ID 26721186
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Role of Phosphatidic Acid Phosphatase Domain Containing 2 (PPAPDC2) In Squalestatin 1-Mediated Activation of the Constitutive Androstane Receptor in Primary Cultured Rat Hepatocytes
,Pant, A;Kocarek, TA;,
Drug Metab. Dispos.
,PubMed ID 26700959
[TR30012]
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Hepatocyte X-box binding protein 1 deficiency increases liver injury in mice fed a high-fat/sugar diet
,null,
American Journal of Physiology - Gastrointestinal and Liver Physiology
,PubMed ID 26472223
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Nrf2 in ischemic neurons promotes retinal vascular regeneration through regulation of semaphorin 6A
,null,
Proceedings of the National Academy of Sciences of the United States of America
,PubMed ID 26621751
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Impaired aldehyde dehydrogenase 1 subfamily member 2A-dependent retinoic acid signaling is related with a mesenchymal-like phenotype and an unfavorable prognosis of head and neck squamous cell carcinoma
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Molecular Cancer
,PubMed ID 26634247
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Suppression of hepatocellular carcinoma cell proliferation by short hairpin RNA of frizzled 2 with Sonazoid-enhanced irradiation.
,null,
International journal of oncology
,PubMed ID 26648389
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Forkhead box protein A1 is a prognostic predictor and promotes tumor growth of gastric cancer
,Ren, H;Zhang, P;Tang, Y;Wu, M;Zhang, W;,
Onco Targets Ther
,PubMed ID 26527889
[TR30012]
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The Histone Methyltransferase Enzyme Enhancer of Zeste Homolog 2 Protects against Podocyte Oxidative Stress and Renal Injury in Diabetes
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Journal of the American Society of Nephrology : JASN
,PubMed ID 26534922
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Repression of HNF1α-mediated transcription by amino-terminal enhancer of split (AES).
,null,
Biochemical and biophysical research communications
,PubMed ID 26549228
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PRL-3 activates mTORC1 in Cancer Progression
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Scientific Reports
,PubMed ID 26597054
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Occludin controls HIV transcription in brain pericytes via regulation of SIRT-1 activation
,null,
The FASEB Journal
,PubMed ID 26601824
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Syntenin controls migration, growth, proliferation, and cell cycle progression in cancer cells
,null,
Frontiers in Pharmacology
,PubMed ID 26539120
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,null,
The Journal of Pharmacology and Experimental Therapeutics
,PubMed ID 26585571
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Circadian Modulation of 8-Oxoguanine DNA Damage Repair
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Scientific Reports
,PubMed ID 26337123
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NPY1–36 and PYY1–36 activate cardiac fibroblasts: an effect enhanced by genetic hypertension and inhibition of dipeptidyl peptidase 4
,null,
American Journal of Physiology - Heart and Circulatory Physiology
,PubMed ID 26371160
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RNAP II Processivity is a Limiting Step for HIV-1 Transcription Independent of Orientation to and Activity of Endogenous Neighboring Promoters
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Virology
,PubMed ID 26379089
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EZH2-mediated loss of miR-622 determines CXCR4 activation in hepatocellular carcinoma
,null,
Nature Communications
,PubMed ID 26404566
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Signaling mechanisms coupled to CXCL12/CXCR4-mediated cellular proliferation are PTEN-dependent
,Begley, LA;Kasina, S;Shah, RB;Macoska, JA;,
Am J Clin Exp Urol
,PubMed ID 26309898
[TR30012]
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FGF8, c-Abl and p300 participate in a pathway that controls stability and function of the ΔNp63α protein
,null,
Human Molecular Genetics
,PubMed ID 25911675
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Aberrant over-expression of COX-1 intersects multiple pro-tumorigenic pathways in high-grade serous ovarian cancer
,null,
Oncotarget
,PubMed ID 25972361
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Elucidation of novel 13-series resolvins that increase with atorvastatin and clear infections
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Nature medicine
,PubMed ID 26236990
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Inhibition of carbonic anhydrase IX (CA9) sensitizes renal cell carcinoma to ionizing radiation.
,null,
Oncology reports
,PubMed ID 26252502
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Reciprocal regulation of two G protein-coupled receptors sensing extracellular concentrations of Ca2+ and H+
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Proceedings of the National Academy of Sciences of the United States of America
,PubMed ID 26261299
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Human mitochondrial MIA40 (CHCHD4) is a component of the Fe-S cluster export machinery.
,null,
The Biochemical journal
,PubMed ID 26275620
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Ras association domain family member 10 suppresses gastric cancer growth by cooperating with GSTP1 to regulate JNK/c-Jun/AP-1 pathway.
,null,
Oncogene
,PubMed ID 26279301
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Dipeptide species regulate p38MAPK–Smad3 signalling to maintain chronic myelogenous leukaemia stem cells
,null,
Nature Communications
,PubMed ID 26289811
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Cellular fibronectin 1 promotes VEGF-C expression, lymphangiogenesis and lymph node metastasis associated with human oral squamous cell carcinoma.
,null,
Clinical experimental metastasis
,PubMed ID 26319373
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Resveratrol inhibits NLRP3 inflammasome activation by preserving mitochondrial integrity and augmenting autophagy.
,null,
Journal of cellular physiology
,PubMed ID 25535911
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MiR-21 promoted proliferation and migration in hepatocellular carcinoma through negative regulation of Navigator-3.
,null,
Biochemical and biophysical research communications
,PubMed ID 26210448
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PBK/TOPK enhances aggressive phenotype in prostate cancer via β-catenin-TCF/LEF-mediated matrix metalloproteinases production and invasion
,null,
Oncotarget
,PubMed ID 25909225
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ATM regulation of IL-8 links oxidative stress to cancer cell migration and invasion
,null,
eLife
,PubMed ID 26030852
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Parecoxib Protects Mouse Cortical Neurons Against OGD/R Induced Neurotoxicity by Up-Regulating Bcl-2.
,null,
Neurochemical research
,PubMed ID 26033681
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PML/RARα-regulated miR-181a/b-cluster targets the tumor suppressor RASSF1A in Acute Promyelocytic Leukemia
,null,
Cancer research
,PubMed ID 26041820
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Physical and functional interactions between a glioma cation channel and integrin-β1 require α-actinin
,null,
American Journal of Physiology - Cell Physiology
,PubMed ID 26108662
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An angiopoietin-like protein 2 autocrine signaling promotes EMT during pancreatic ductal carcinogenesis
,null,
Oncotarget
,PubMed ID 25360865
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A novel role for drebrin in regulating progranulin bioactivity in bladder cancer
,null,
Oncotarget
,PubMed ID 25839164
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Redox signalling to nuclear regulatory proteins by reactive oxygen species contributes to oestrogen-induced growth of breast cancer cells
,null,
British Journal of Cancer
,PubMed ID 25965299
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Stk38 protein kinase preferentially inhibits TLR9-activated inflammatory responses by promoting MEKK2 ubiquitination in macrophages.
,null,
Nature communications
,PubMed ID 25981615
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Kallikrein-related peptidase 6 regulates epithelial-to-mesenchymal transition and serves as prognostic biomarker for head and neck squamous cell carcinoma patients
,null,
Molecular Cancer
,PubMed ID 25990935
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RIPK1 regulates survival of human melanoma cells upon endoplasmic reticulum stress through autophagy
,null,
Autophagy
,PubMed ID 26018731
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RARRES3 suppressed metastasis through suppression of MTDH to regulate epithelial-mesenchymal transition in colorectal cancer
,null,
American Journal of Cancer Research
,PubMed ID 26269758
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Regulation of Protein Quality Control by UBE4B and LSD1 through p53-Mediated Transcription
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PLoS Biology
,PubMed ID 25837623
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Cancer-Associated Oxidase ERO1-α Regulates the Expression of MHC Class I Molecule via Oxidative Folding.
,null,
Journal of immunology (Baltimore, Md. : 1950)
,PubMed ID 25870246
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B7-H3 promotes aggression and invasion of hepatocellular carcinoma by targeting epithelial-to-mesenchymal transition via JAK2/STAT3/Slug signaling pathway
,null,
Cancer Cell International
,PubMed ID 25908926
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Bik Mediates Caspase-Dependent Cleavage of Viral Proteins to Promote Influenza A Virus Infection
,null,
American Journal of Respiratory Cell and Molecular Biology
,PubMed ID 26437021
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Human T-Cell Leukemia Virus Type 1 (HTLV-1) Tax Requires CADM1/TSLC1 for Inactivation of the NF-κB Inhibitor A20 and Constitutive NF-κB Signaling
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PLoS Pathogens
,PubMed ID 25774694
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Cavin-1 and Caveolin-1 are both required to support cell proliferation, migration and anchorage-independent cell growth in rhabdomyosarcoma.
,null,
Laboratory investigation; a journal of technical methods and pathology
,PubMed ID 25822667
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Biologic Roles of Estrogen Receptor-β and Insulin-Like Growth Factor-2 in Triple-Negative Breast Cancer
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BioMed Research International
,PubMed ID 25874233
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Mechanisms of tumor-promoting activities of nicotine in lung cancer: synergistic effects of cell membrane and mitochondrial nicotinic acetylcholine receptors
,null,
BMC Cancer
,PubMed ID 25885699
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Acyl-CoA synthetase 1 deficiency alters cardiolipin species and impairs mitochondrial function
,null,
Journal of Lipid Research
,PubMed ID 26136511
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Der Einfluss des Mismatch Reparaturfaktors hMSH2 auf distinkte Reparaturwege der DNA Doppelstrangbruch Reparatur
,Schwan, A;,
thesis
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BMX negatively regulates BAK function thereby increasing apoptotic resistance to chemotherapeutic drugs
,null,
Cancer research
,PubMed ID 25649765
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Knockdown of the host cellular protein transportin 3 attenuates prototype foamy virus infection.
,null,
Bioscience, biotechnology, and biochemistry
,PubMed ID 25660973
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Adenosine A1 receptor activation modulates human equilibrative nucleoside transporter 1 (hENT1) activity via PKC-mediated phosphorylation of serine-281.
,null,
Cellular signalling
,PubMed ID 25725289
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Gene silencing of non-obese diabetic receptor family (NLRP3) protects against the sepsis-induced hyper-bile acidaemia in a rat model
,null,
Clinical and Experimental Immunology
,PubMed ID 25228381
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PLK1 Inhibition Down-regulates Polycomb Group Protein BMI1 via Modulation of the miR-200c/141 Cluster *
,null,
The Journal of Biological Chemistry
,PubMed ID 25505268
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The Roles of Akt Isoforms in the Regulation of Podosome Formation in Fibroblasts and Extracellular Matrix Invasion
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Cancers
,PubMed ID 25575302
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MUC1 Protein Induces Urokinase-type Plasminogen Activator (uPA) by Forming a Complex with NF-κB p65 Transcription Factor and Binding to the uPA Promoter, Leading to Enhanced Invasiveness of Cancer Cells *
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The Journal of Biological Chemistry
,PubMed ID 25371209
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STING agonists induce an innate antiviral immune response against hepatitis B virus
,Guo, F;Han, Y;Zhao, X;Wang, J;Liu, F;Xu, C;Wei, L;Jiang, JD;Block, TM;Guo, JT;Chang, J;,
Antimicrob. Agents Chemother.
,PubMed ID 25512416
[TR30012]
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Pea3 expression promotes the invasive and metastatic potential of colorectal carcinoma
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World Journal of Gastroenterology : WJG
,PubMed ID 25516649
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Sunitinib dose-escalation overcomes transient resistance in clear cell renal cell carcinoma and is associated with epigenetic modifications
,null,
Molecular cancer therapeutics
,PubMed ID 25519701
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Nlrx1 regulates neuronal cell death
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Molecular Brain
,PubMed ID 25540124
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Macrophage SR-BI mediates efferocytosis via Src/PI3K/Rac1 signaling and reduces atherosclerotic lesion necrosis [S]
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Journal of Lipid Research
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MS-275 sensitizes osteosarcoma cells to Fas ligand-induced cell death by increasing the localization of Fas in membrane lipid rafts
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