JIP3 (MAPK8IP3) Human shRNA Plasmid Kit (Locus ID 23162)
CAT#: TG311574
MAPK8IP3 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided
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CNY 4,790.00
货期*
现货
规格
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Specifications
Product Data | |
Product Name | JIP3 (MAPK8IP3) Human shRNA Plasmid Kit (Locus ID 23162) |
Locus ID | 23162 |
UniProt ID | Q9UPT6 |
Synonyms | JIP-3; JIP3; JSAP1; NEDBA; syd; SYD2 |
Vector | pGFP-V-RS |
Format | Retroviral plasmids |
Kit Components | MAPK8IP3 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 23162). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free. |
RefSeq | NM_001040439, NM_001318852, NM_015133, NM_033392, NM_001040439.1, NM_015133.1, NM_015133.2, NM_015133.3, NM_015133.4, BC087861, BC137123, BC137124, BC144486, BC150266, BM791368, NM_001040439.2, NM_015133.5 |
Summary | The protein encoded by this gene shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart of this gene is found to regulate synaptic vesicle transport possibly by integrating JNK signaling and kinesin-1 transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008] |
shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
Performance Guaranteed | OriGene guarantees that the sequences in the shRNA expression cassettes are verified to correspond to the target gene with 100% identity. One of the four constructs at minimum are guaranteed to produce 70% or more gene expression knock-down provided a minimum transfection efficiency of 80% is achieved. Western Blot data is recommended over qPCR to evaluate the silencing effect of the shRNA constructs 72 hrs post transfection. To properly assess knockdown, the gene expression level from the included scramble control vector must be used in comparison with the target-specific shRNA transfected samples. For non-conforming shRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the shRNA kit. To arrange for a free replacement with newly designed constructs, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled shRNA control (Western Blot data preferred). |
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