SIVA (SIVA1) (NM_021709) Human Recombinant Protein

CAT#: TP761811

Purified recombinant protein of Human SIVA1, apoptosis-inducing factor (SIVA1), transcript variant 2, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug



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CNY 2,040.00


货期*
2周

规格
    • 50 ug

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经常一起买 (1)
SIVA1 mouse monoclonal antibody, clone OTI2F8 (formerly 2F8)
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Specifications

Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence encoding human full-length SIVA1
Tag N-GST and C-His
Predicted MW 39.6 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, pH 8.0, 8 M urea
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_068355
Locus ID 10572
UniProt ID O15304
Refseq Size 595
Cytogenetics 14q32.33
Refseq ORF 330
Synonyms CD27BP; SIVA; Siva-1; Siva-2
Summary This gene encodes an E3 ubiquitin ligase that regulates cell cycle progression, cell proliferation and apoptosis. The N-terminus of this protein binds to the cytoplasmic tail of the CD27 antigen, a member of the tumor necrosis factor receptor (TNFR) superfamily. In response to UV radiation-induced DNA damage, this protein has been shown to mediate the ubiquitination of proliferating cell nuclear antigen (PCNA), an important step in translesion DNA synthesis. [provided by RefSeq, Sep 2018]
Protein Families Druggable Genome
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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