M-CSF (CSF1) (NM_172212) Human Recombinant Protein

CAT#: TP723739

Purified recombinant protein of Human colony stimulating factor 1 (macrophage) (CSF1), transcript variant 4



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CNY 3,560.00


货期*
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规格
    • 10 ug

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经常一起买 (1)
CSF1 mouse monoclonal antibody, clone OTI2D6 (formerly 2D6)
    • 100 ul

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Specifications

Product Data
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence
Human M-CSF, the region of Glu33-Ser190, from gene Accession# NM_172212.2
Tag Tag Free
Predicted MW 20.6 kDa
Concentration lot specific
Purity >98%, as determined by Coomassie stained SDS-PAGE.
Buffer 1 x PBS
Storage Store at -80°C.
Stability Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
Bioactivity The ED50 is 0.5 - 2 ng/ml, corresponding to a specific activity of 0.5 - 2 x 10^6 units/mg, determined by M-NFS60 cell proliferation induced by human M-CSF in a dose dependent manner.
Endotoxin Less than 0.01 ng per µg protein as determined by the LAL method
Reference Data
RefSeq NP_757351
Locus ID 1435
UniProt ID P09603
Refseq Size 2772
Cytogenetics 1p13.3
Refseq ORF 1662
Synonyms CSF-1; MCSF
Summary The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction, Hematopoietic cell lineage
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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