ERBB2 Human Recombinant Protein

CAT#: TP721315

Human HER2 Protein (C-His-Avi)

Size: 25 ug 100 ug



  View other "Her2" proteins (18)

Need it in bulk or customized?
Get a free quote

CNY 2,450.00


货期*
详询

规格
    • 25 ug

Product images

经常一起买 (1)
ERBB2 mouse monoclonal antibody, clone OTI4F10 (formerly 4F10)
    • 100 ul

CNY 1,999.00
CNY 2,700.00

Specifications

Product Data
Species Human
Expression Host CHO
Expression cDNA Clone or AA Sequence
Tag C-His-Avi
Predicted MW The protein has a predicted molecular weight of 73 kDa and migrates at approximately 80 kDa on SDS-PAGE with DTT-reduced conditions.
Concentration 25µg size is bottled at 0.2mg/mL concentration. 100 µg size is bottled at lot specific concentration.
Purity >90%
Buffer 1xPBS buffer, pH7.4
Preparation Affinity Ni-NTA
Applications ELISA
Storage An unopened vial can be stored at 4°C for 2 weeks or at -20°C and below for six months. This stock solution should be aliquoted and stored at ≤ -70°C to minimize the freeze/thaw cycles.
Stability 6 Months
Bioactivity Positive

The definition of the active protein (purified and biotinylated) is defined as the protein that can bind to its biological receptor/ligand. For conjugated protein, it is defined with its function to bind to the ScFv of the active CAR-transfected cells in flow cytometry test.
Reference Data
RefSeq NP_004439.2
Locus ID 2064
UniProt ID P04626
Summary Human epithelial growth factor receptor 2 (HER2), also named ErbB2/Neu receptor, is a member of the epidermal growth factor receptor (EGFR; also known as ErbB) family of receptor tyrosine kinases. In human, this family are consisted of four members: HER1 (EGFR, ERBB1), HER2 (ERBB2), HER3 (ERBB3) and HER4 (ERBB4). The HER family proteins are type I transmembrane growth factor receptors that function to activate intracellular signaling pathways in response to extracellular signals. Their structure consists of an extracellular ligand binding domain, a transmembrane domain, and an intracellular tyrosine kinase domain. Unlike other members of the family, HER2 lacks ligand binding activity and its signaling function is engaged by its ligand-bound heterodimeric partners. Its expression has a close relationship with various tumors. Its overexpression is found in malignant tumors, such as breast, ovarian, gastric, and colorectal cancers.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Documents

Other Versions

Customer Reviews 
Loading...