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PKM2 (PKM) (NM_002654) Human Recombinant Protein
CAT＃: TP721212
Purified recombinant protein of Human pyruvate kinase, muscle (PKM2), transcript variant 1
View other "PKM2" proteins (12)
|
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CNY 3,850.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Species | Human |
| Expression Host | E. coli |
| Expression cDNA Clone or AA Sequence |
Ser2-Pro531
|
| Tag | N-His |
| Predicted MW | 59 kDa |
| Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | Provided lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl |
| Storage | Store at -80°C. |
| Stability | Stable for at least 3 months from date of receipt under proper storage and handling conditions. |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
| Reference Data | |
| RefSeq | NP_002645 |
| Locus ID | 5315 |
| UniProt ID | P14618, V9HWB8 |
| Refseq Size | 2516 |
| Cytogenetics | 15q23 |
| Refseq ORF | 1593 |
| Synonyms | CTHBP; HEL-S-30; OIP3; p58; PK3; PKM2; TCB; THBP1 |
| Summary | This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. [provided by RefSeq, May 2011] |
| Protein Families | Druggable Genome |
| Protein Pathways | Glycolysis / Gluconeogenesis, Metabolic pathways, Purine metabolism, Pyruvate metabolism, Type II diabetes mellitus |
Citations (1)
| The use of this Proteins has been cited in the following citations: |
|---|
|
The HIF-1α antisense long non-coding RNA drives a positive feedback loop of HIF-1α mediated transactivation and glycolysis
,Zheng, F;Chen, J;Zhang, X;Wang, Z;Chen, J;Lin, X;Huang, H;Fu, W;Liang, J;Wu, W;Li, B;Yao, H;Hu, H;Song, E;,
Nature communications
,PubMed ID 33637716
[PKM]
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Resources
| 蛋白相关资源 |
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC405537 | PKM HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1,470.00 |
|
| LC405538 | PKM HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1,470.00 |
|
| LC419188 | PKM HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY405537 | Transient overexpression lysate of pyruvate kinase, muscle (PKM2), transcript variant 2 |
CNY 4,840.00 |
|
| LY405538 | Transient overexpression lysate of pyruvate kinase, muscle (PKM2), transcript variant 3 |
CNY 4,840.00 |
|
| LY419188 | Transient overexpression lysate of pyruvate kinase, muscle (PKM2), transcript variant 1 |
CNY 3,080.00 |
|
| PH301855 | PKM2 MS Standard C13 and N15-labeled recombinant protein (NP_002645) |
CNY 19,520.00 |
|
| PH319382 | PKM2 MS Standard C13 and N15-labeled recombinant protein (NP_872270) |
CNY 19,520.00 |
|
| PH322698 | PKM2 MS Standard C13 and N15-labeled recombinant protein (NP_872271) |
CNY 19,520.00 |
|
| TP301855 | Recombinant protein of human pyruvate kinase, muscle (PKM2), transcript variant 1, 20 µg |
CNY 2,900.00 |
|
| TP319382 | Recombinant protein of human pyruvate kinase, muscle (PKM2), transcript variant 2, 20 µg |
CNY 2,900.00 |
|
| TP322698 | Recombinant protein of human pyruvate kinase, muscle (PKM2), transcript variant 3, 20 µg |
CNY 2,900.00 |
