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STAT3 (NM_003150) Human Recombinant Protein
CAT＃: TP720889
Purified recombinant protein of Human signal transducer and activator of transcription 3 (acute-phase response factor) (STAT3), transcript variant 2
View other "STAT3" proteins (8)
|
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CNY 1,800.00
Product images
CNY 1,999.00
CNY 2,700.00
热销推荐Specifications
| Product Data | |
| Species | Human |
| Expression cDNA Clone or AA Sequence |
Met1-Asn175
|
| Tag | C-His |
| Predicted MW | 21.8 kDa |
| Concentration | lot specific |
| Purity | >95% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4. |
| Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| Stability | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
| Endotoxin | Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg) |
| Reference Data | |
| RefSeq | |
| Locus ID | 6774 |
| UniProt ID | P40763 |
| Cytogenetics | 17q21.2 |
| Synonyms | ADMIO; ADMIO1; APRF; HIES |
| Summary | The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. This gene also plays a role in regulating host response to viral and bacterial infections. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. [provided by RefSeq, Aug 2020] |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | Acute myeloid leukemia, Adipocytokine signaling pathway, Chemokine signaling pathway, Jak-STAT signaling pathway, Pancreatic cancer, Pathways in cancer |
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Resources
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC403728 | STAT3 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1,470.00 |
|
| LC408332 | STAT3 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY403728 | Transient overexpression lysate of signal transducer and activator of transcription 3 (acute-phase response factor) (STAT3), transcript variant 3 |
CNY 4,840.00 |
|
| LY408332 | Transient overexpression lysate of signal transducer and activator of transcription 3 (acute-phase response factor) (STAT3), transcript variant 1 |
CNY 3,080.00 |
|
| PH312394 | STAT3 MS Standard C13 and N15-labeled recombinant protein (NP_998827) |
CNY 19,520.00 |
|
| PH315836 | STAT3 MS Standard C13 and N15-labeled recombinant protein (NP_644805) |
CNY 19,520.00 |
|
| TP312394 | Recombinant protein of human signal transducer and activator of transcription 3 (acute-phase response factor) (STAT3), transcript variant 3, 20 µg |
CNY 2,900.00 |
|
| TP315836 | Recombinant protein of human signal transducer and activator of transcription 3 (acute-phase response factor) (STAT3), transcript variant 1, 20 µg |
CNY 2,900.00 |
