CD32B (FCGR2B) (NM_001002275) Human Recombinant Protein

Specifications

Product Data
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) Thr43-Pro217
Tag	C-His
Predicted MW	20.64 kDa
Concentration	lot specific
Purity	>95% as determined by SDS-PAGE and Coomassie blue staining
Buffer	Lyophilized from a 0.2 um filtered solution of PBS, pH7.4
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Stability	Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Endotoxin	Endotoxin level is < 0.1 ng/µg of protein (< 1 EU/µg)
Reference Data
RefSeq	NP_001002275
Locus ID	2213
UniProt ID	P31994
Refseq Size	1630
Cytogenetics	1q23.3
Refseq ORF	930
Synonyms	CD32; CD32B; FCG2; FCGR2; FCGR2C; FcRII-c; IGFR2
Summary	The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
Protein Families	ES Cell Differentiation/IPS, Transmembrane
Protein Pathways	B cell receptor signaling pathway, Fc gamma R-mediated phagocytosis, Systemic lupus erythematosus

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