CD32B (FCGR2B) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Human placenta tissue IHC: 50-200 Positive control: Human liver cancer Predicted cell location: Cytoplasm
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human FCGR2B
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	34 kDa
Gene Name	Fc fragment of IgG receptor IIb
Database Link	NP_001002275 Entrez Gene 2213 Human UniProt ID P31994
Background	The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.
Synonyms	CD32; CD32B; FCG2; FCGR2; IGFR2
Reference Data
Protein Families	ES Cell Differentiation/IPS, Transmembrane
Protein Pathways	B cell receptor signaling pathway, Fc gamma R-mediated phagocytosis, Systemic lupus erythematosus

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