United States
Germany
Japan
United Kingdom
China
p53 (TP53) (NM_000546) Human Recombinant Protein
CAT＃: TP701001
Purified recombinant protein of human tumor protein P53 (TP53), transcript variant 1, mutant (Y220C), expressed in HEK293 cells, 20ug
View other "p53" proteins (16)
|
Need it in bulk or customized? Get a free quote |
Avi-tag Biotinylated Protein Get a free quote |
CNY 6,650.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Species | Human |
| Expression Host | HEK293T |
| Expression cDNA Clone or AA Sequence |
A DNA sequence from TrueORF clone, RC400052, encoding human TP53 mutant Y220C
|
| Tag | C-Myc/DDK |
| Predicted MW | 43.6 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Reference Data | |
| RefSeq | NP_000537 |
| Locus ID | 7157 |
| UniProt ID | P04637 |
| Refseq Size | 2629 |
| Cytogenetics | 17p13.1 |
| Refseq ORF | 1182 |
| Synonyms | BCC7; BMFS5; LFS1; P53; TRP53 |
| Summary | This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016] |
| Protein Families | Druggable Genome, Stem cell - Pluripotency, Transcription Factors |
| Protein Pathways | Amyotrophic lateral sclerosis (ALS), Apoptosis, Basal cell carcinoma, Bladder cancer, Cell cycle, Chronic myeloid leukemia, Colorectal cancer, Endometrial cancer, Glioma, Huntington's disease, MAPK signaling pathway, Melanoma, Neurotrophin signaling pathway, Non-small cell lung cancer, p53 signaling pathway, Pancreatic cancer, Pathways in cancer, Prostate cancer, Small cell lung cancer, Thyroid cancer, Wnt signaling pathway |
Citations (1)
| The use of this Proteins has been cited in the following citations: |
|---|
|
Direct Detection of Alternative Open Reading Frames Translation Products in Human Significantly Expands the Proteome
,null,
PLoS ONE
,PubMed ID 23950983
[TP53]
|
Documents
| FAQs |
| SDS |
Resources
| 蛋白相关资源 |
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC400186 | TP53 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC426652 | TP53 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC426653 | TP53 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC426654 | TP53 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY400186 | Transient overexpression lysate of tumor protein p53 (TP53), transcript variant 1 |
CNY 3,080.00 |
|
| LY426652 | Transient overexpression lysate of tumor protein p53 (TP53), transcript variant 2 |
CNY 3,080.00 |
|
| LY426653 | Transient overexpression lysate of tumor protein p53 (TP53), transcript variant 4 |
CNY 3,080.00 |
|
| LY426654 | Transient overexpression lysate of tumor protein p53 (TP53), transcript variant 3 |
CNY 3,080.00 |
|
| PH300003 | TP53 MS Standard C13 and N15-labeled recombinant protein (NP_000537) |
CNY 19,520.00 |
|
| PH325502 | TP53 MS Standard C13 and N15-labeled recombinant protein (NP_001119586) |
CNY 14,250.00 |
|
| PH325604 | TP53 MS Standard C13 and N15-labeled recombinant protein (NP_001119584) |
CNY 19,520.00 |
|
| TP300003 | Recombinant protein of human tumor protein p53 (TP53), transcript variant 1, 20 µg |
CNY 2,900.00 |
|
| TP325502 | Purified recombinant protein of Homo sapiens tumor protein p53 (TP53), transcript variant 3, 20 µg |
CNY 2,900.00 |
|
| TP325604 | Recombinant protein of human tumor protein p53 (TP53), transcript variant 2, 20 µg |
CNY 2,900.00 |
|
| TP710022 | Recombinant protein of human tumor protein p53 (TP53), transcript variant 1, full length, with C-terminal DDK tag, expressed in sf9 cells. |
CNY 4,020.00 |
|
| TP750119 | Purified recombinant protein of Human tumor protein p53 (TP53), transcript variant 1, full length, N-terminal His and GST tag, expressed in E. coli, 50ug |
CNY 2,000.00 |
