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HP1 alpha (CBX5) (NM_001127321) Human Recombinant Protein
CAT＃: TP325208
Recombinant protein of human chromobox homolog 5 (HP1 alpha homolog, Drosophila) (CBX5), transcript variant 2, 20 µg
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Specifications
| Product Data | |
| Species | Human |
| Expression Host | HEK293T |
| Expression cDNA Clone or AA Sequence |
>RC225208 protein sequence
Red=Cloning site Green=Tags(s) MGKKTKRTADSSSSEDEEEYVVEKVLDRRVVKGQVEYLLKWKGFSEEHNTWEPEKNLDCPELISEFMKKY KKMKEGENNKPREKSESNKRKSNFSNSADDIKSKKKREQSNDIARGFERGLEPEKIIGATDSCGDLMFLM KWKDTDEADLVLAKEANVKCPQIVIAFYEERLTWHAYPEDAENKEKETAKS TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Tag | C-Myc/DDK |
| Predicted MW | 22 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Reference Data | |
| RefSeq | NP_001120793 |
| Locus ID | 23468 |
| UniProt ID | P45973 |
| Refseq Size | 11525 |
| Cytogenetics | 12q13.13 |
| Refseq ORF | 573 |
| Synonyms | HEL25; HP1; HP1A |
| Summary | This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008] |
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Resources
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC402149 | CBX5 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC426744 | CBX5 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC426745 | CBX5 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY402149 | Transient overexpression lysate of chromobox homolog 5 (HP1 alpha homolog, Drosophila) (CBX5), transcript variant 3 |
CNY 3,080.00 |
|
| LY426744 | Transient overexpression lysate of chromobox homolog 5 (HP1 alpha homolog, Drosophila) (CBX5), transcript variant 2 |
CNY 3,080.00 |
|
| LY426745 | Transient overexpression lysate of chromobox homolog 5 (HP1 alpha homolog, Drosophila) (CBX5), transcript variant 1 |
CNY 3,080.00 |
|
| PH301515 | CBX5 MS Standard C13 and N15-labeled recombinant protein (NP_036249) |
CNY 19,520.00 |
|
| PH325208 | CBX5 MS Standard C13 and N15-labeled recombinant protein (NP_001120793) |
CNY 19,520.00 |
|
| TP301515 | Recombinant protein of human chromobox homolog 5 (HP1 alpha homolog, Drosophila) (CBX5), transcript variant 3, 20 µg |
CNY 2,900.00 |
|
| TP760487 | Purified recombinant protein of Human chromobox homolog 5 (CBX5), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug |
CNY 2,040.00 |
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