HP1 alpha (CBX5) (NM_001127321) Human Mass Spec Standard

CAT#: PH325208

CBX5 MS Standard C13 and N15-labeled recombinant protein (NP_001120793)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description CBX5 MS Standard C13 and N15-labeled recombinant protein (NP_001120793)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC225208
Predicted MW 22.2 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001120793
RefSeq Size 11525
RefSeq ORF 573
Synonyms HEL25; HP1; HP1A
Locus ID 23468
Cytogenetics 12q13.13
Summary This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
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