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PLAUR (NM_002659) Human Recombinant Protein
CAT＃: TP301222
Recombinant protein of human plasminogen activator, urokinase receptor (PLAUR), transcript variant 1, 20 µg
View other "PLAUR" proteins (10)
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| Cited in 1 publication. |
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CNY 600.00
Specifications
| Product Data | |
| Species | Human |
| Expression Host | HEK293T |
| Expression cDNA Clone or AA Sequence |
>RC201222 protein sequence
Red=Cloning site Green=Tags(s) MGHPPLLPLLLLLHTCVPASWGLRCMQCKTNGDCRVEECALGQDLCRTTIVRLWEEGEELELVEKSCTHS EKTNRTLSYRTGLKITSLTEVVCGLDLCNQGNSGRAVTYSRSRYLECISCGSSDMSCERGRHQSLQCRSP EEQCLDVVTHWIQEGEEGRPKDDRHLRGCGYLPGCPGSNGFHNNDTFHFLKCCNTTKCNEGPILELENLP QNGRQCYSCKGNSTHGCSSEETFLIDCRGPMNQCLVATGTHEPKNQSYMVRGCATASMCQHAHLGDAFSM NHIDVSCCTKSGCNHPDLDVQYRSGAAPQPGPAHLSLTITLLMTARLWGGTLLWT TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Tag | C-Myc/DDK |
| Predicted MW | 34.6 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Bioactivity | Dimerization assay (confocal) (PMID: 25418095) |
| Reference Data | |
| RefSeq | NP_002650 |
| Locus ID | 5329 |
| UniProt ID | Q03405 |
| Refseq Size | 1570 |
| Cytogenetics | 19q13.31 |
| Refseq ORF | 1005 |
| Synonyms | CD87; U-PAR; UPAR; URKR |
| Summary | This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq, Jul 2008] |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | Complement and coagulation cascades |
Citations (1)
| The use of this Proteins has been cited in the following citations: |
|---|
|
Ligand binding alters dimerization and sequestering of urokinase receptors in raft-mimicking lipid mixtures
,Ge, Y;Siegel, AP;Jordan, R;Naumann, CA;,
Biophys. J.
,PubMed ID 25418095
[PLAUR]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC400943 | PLAUR HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC423709 | PLAUR HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC423710 | PLAUR HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY400943 | Transient overexpression lysate of plasminogen activator, urokinase receptor (PLAUR), transcript variant 1 |
CNY 3,080.00 |
|
| LY423709 | Transient overexpression lysate of plasminogen activator, urokinase receptor (PLAUR), transcript variant 2 |
CNY 3,080.00 |
|
| LY423710 | Transient overexpression lysate of plasminogen activator, urokinase receptor (PLAUR), transcript variant 3 |
CNY 3,080.00 |
|
| PH301222 | PLAUR MS Standard C13 and N15-labeled recombinant protein (NP_002650) |
CNY 19,520.00 |
|
| PH317929 | PLAUR MS Standard C13 and N15-labeled recombinant protein (NP_001005376) |
CNY 14,250.00 |
|
| TP317929 | Purified recombinant protein of Homo sapiens plasminogen activator, urokinase receptor (PLAUR), transcript variant 2, 20 µg |
CNY 2,900.00 |
|
| TP720329 | Recombinant protein of human plasminogen activator, urokinase receptor (PLAUR), transcript variant 2 |
CNY 3,140.00 |
