PPOX (NM_001122764) Human Mass Spec Standard

CAT#: PH325811

PPOX MS Standard C13 and N15-labeled recombinant protein (NP_001116236)



  View other "PPOX" proteins (7)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Rabbit Polyclonal Anti-PPOX Antibody
    • 100 ul

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Transient overexpression lysate of protoporphyrinogen oxidase (PPOX), nuclear gene encoding mitochondrial protein, transcript variant 1
    • 100 ug

CNY 3,080.00

Specifications

Product Data
Description PPOX MS Standard C13 and N15-labeled recombinant protein (NP_001116236)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC225811
Predicted MW 50.8 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001116236
RefSeq Size 1777
RefSeq ORF 1431
Synonyms PPO; V290M; VP
Locus ID 5498
Cytogenetics 1q23.3
Summary This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
Protein Pathways Metabolic pathways, Porphyrin and chlorophyll metabolism
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