SPAG11B (NM_058201) Human Mass Spec Standard

Specifications

Product Data
Description	SPAG11B MS Standard C13 and N15-labeled recombinant protein (NP_478108)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC224764
Predicted MW	12.1 kDa
Protein Sequence	Sequence Link (showhide) >RC224764 representing NM_058201 Red=Cloning site Green=Tags(s) MRQRLLPSVTSLLLVALLFPGSSQARHVNHSATEALGELRERAPGQGTNGFQLLRHAVKRDLLPPRTPPY QGDVPPGIRNTICRMQQGICRLFFCHSGEKKRDICSDPWNRCCVSNTDEEGKEKPEMDGRSGI TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_478108
RefSeq Size	718
RefSeq ORF	399
Synonyms	EDDM2B; EP2; EP2C; EP2D; HE2; HE2C; SPAG11; SPAG11A
Locus ID	10407
Cytogenetics	8p23.1
Summary	This gene encodes several androgen-dependent, epididymis-specific secretory proteins. The specific functions of these proteins have not been determined, but they are thought to be involved in sperm maturation. Some of the isoforms contain regions of similarity to beta-defensins, a family of antimicrobial peptides. The gene is located on chromosome 8p23 near the defensin gene cluster. Alternative splicing of this gene results in seven transcript variants encoding different isoforms. Two different N-terminal and five different C-terminal protein sequences are encoded by the splice variants. Two additional variants have been described, but their full length sequences have not been determined. [provided by RefSeq, Jul 2008]
Protein Families	Secreted Protein

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