TCF4 (NM_001083962) Human Mass Spec Standard

CAT#: PH324345

TCF4 MS Standard C13 and N15-labeled recombinant protein (NP_001077431)



  View other "TCF4" proteins (8)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Rabbit Polyclonal Anti-TCF4 Antibody
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Transient overexpression lysate of transcription factor 4 (TCF4), transcript variant 2
    • 100 ug

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Specifications

Product Data
Description TCF4 MS Standard C13 and N15-labeled recombinant protein (NP_001077431)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC224345
Predicted MW 71.6 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001077431
RefSeq Size 8332
RefSeq ORF 2013
Synonyms bHLHb19; CDG2T; E2-2; FECD3; ITF-2; ITF2; PTHS; SEF-2; SEF2; SEF2-1; SEF2-1A; SEF2-1B; SEF2-1D; TCF-4
Locus ID 6925
Cytogenetics 18q21.2
Summary This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. In addition, an intronic CTG repeat normally numbering 10-37 repeat units can expand to >50 repeat units and cause Fuchs endothelial corneal dystrophy. Multiple alternatively spliced transcript variants that encode different proteins have been described. [provided by RefSeq, Jul 2016]
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors
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