Exosome Component 9 (EXOSC9) (NM_001034194) Human Mass Spec Standard

Specifications

Product Data
Description	EXOSC9 MS Standard C13 and N15-labeled recombinant protein (NP_001029366)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC223537
Predicted MW	50.6 kDa
Protein Sequence	Sequence Link (showhide) >RC223537 representing NM_001034194 Red=Cloning site Green=Tags(s) MKETPLSNCERRFLLRAIEEKKRLDGRQTYDYRNIRISFGTDYGCCIVELGKTRVLGQVSCELVSPKLNR ATEGILFFNLELSQMAAPAFEPGRQSDLLVKLNRLMERCLRNSKCIDTESLCVVAGEKVWQIRVDLHLLN HDGNIIDAASIAAIVALCHFRRPDVSVQGDEVTLYTPEERDPVPLSIHHMPICVSFAFFQQGTYLLVDPN EREERVMDGLLVIAMNKHREICTIQSSGGIMLLKDQVLRCSKIAGVKVAEITELILKALENDQKVRKEGG KFGFAESIANQRITAFKMEKAPIDTSDVEEKAEEIIAEAEPPSEVVSTPVLWTPGTAQIGEGVENSWGDL EDSEKEDDEGGGDQAIILDGIKMDTGVEVSDIGSQELGFHHVGQTGLEFLTSDAPIILSDSEEEEMIILE PDKNPKKIRTQTTSAKQEKAPSKKPVKRRKKKRAAN TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_001029366
RefSeq Size	1644
RefSeq ORF	1368
Synonyms	p5; p6; PCH1D; PM/Scl-75; PMSCL1; RRP45; Rrp45p
Locus ID	5393
Cytogenetics	4q27
Summary	This gene encodes a component of the human exosome, a exoribonuclease complex which processes and degrades RNA in the nucleus and cytoplasm. This component may play a role in mRNA degradation and the polymyositis/scleroderma autoantigen complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
Protein Families	Stem cell - Pluripotency
Protein Pathways	RNA degradation

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