SH3BP5 (NM_001018009) Human Mass Spec Standard

CAT#: PH321321

SH3BP5 MS Standard C13 and N15-labeled recombinant protein (NP_001018009)



  View other "SH3BP5" proteins (8)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
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Specifications

Product Data
Description SH3BP5 MS Standard C13 and N15-labeled recombinant protein (NP_001018009)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC221321
Predicted MW 50.4 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001018009
RefSeq Size 3203
RefSeq ORF 1365
Synonyms SAB; SH3BP-5
Locus ID 9467
Cytogenetics 3p25.1
Summary Functions as guanine nucleotide exchange factor (GEF) with specificity for RAB11A and RAB25 (PubMed:26506309, PubMed:30217979). Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death.[UniProtKB/Swiss-Prot Function]
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