NM23A (NME1) (NM_198175) Human Mass Spec Standard

CAT#: PH320517

NME1 MS Standard C13 and N15-labeled recombinant protein (NP_937818)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
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Transient overexpression lysate of non-metastatic cells 1, protein (NM23A) expressed in (NME1), transcript variant 2
    • 100 ug

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Specifications

Product Data
Description NME1 MS Standard C13 and N15-labeled recombinant protein (NP_937818)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC220517
Predicted MW 19.5 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_937818
RefSeq Size 1031
RefSeq ORF 531
Synonyms AWD; GAAD; NB; NBS; NDKA; NDPK-A; NDPKA; NM23; NM23-H1
Locus ID 4830
Cytogenetics 17q21.33
Summary This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Stem cell - Pluripotency
Protein Pathways Metabolic pathways, Purine metabolism, Pyrimidine metabolism
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