GnRH (GNRH1) (NM_001083111) Human Mass Spec Standard

Specifications

Product Data
Description	GNRH1 MS Standard C13 and N15-labeled recombinant protein (NP_001076580)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC219734
Predicted MW	10.4 kDa
Protein Sequence	Sequence Link (showhide) >RC219734 protein sequence Red=Cloning site Green=Tags(s) MKPIQKLLAGLILLTWCVEGCSSQHWSYGLRPGGKRDAENLIDSFQEIVKEVGQLAETQRFECTTHQPRS PLRDLKGALESLIEEETGQKKI TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_001076580
RefSeq Size	1297
RefSeq ORF	276
Synonyms	GNRH; GRH; LHRH; LNRH
Locus ID	2796
Cytogenetics	8p21.2
Summary	This gene encodes a preproprotein that is proteolytically processed to generate a peptide that is a member of the gonadotropin-releasing hormone (GnRH) family of peptides. Alternative splicing results in multiple transcript variants, at least one of which is secreted and then cleaved to generate gonadoliberin-1 and GnRH-associated peptide 1. Gonadoliberin-1 stimulates the release of luteinizing and follicle stimulating hormones, which are important for reproduction. Mutations in this gene are associated with hypogonadotropic hypogonadism. [provided by RefSeq, Nov 2015]
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	GnRH signaling pathway

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